DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Ligand Name
(4S)-8-(methanesulfonyl)-2,3-dimethyl-6-{2-[1-methyl-3-(pyrrolidin-1-yl)-1H-1,2,4-triazol-5-yl]ethyl}imidazo[1,2-b]pyridazine
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
WXWZEOMYBKHZCL-UHFFFAOYSA-N
SMILES
Cc1c(n2c(n1)c(cc(n2)CCc3nc(nn3C)N4CCCC4)S(=O)(=O)C)C
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 5SH3
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Color Legend
Unassigned regionsLigand / hetero atomse5sh3A1e5sh3B1e5sh3C1e5sh3D1
ECOD domains from experimental PDB structures interacting with ligand J2L
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q9Y233n/aJ2L5sh3e5sh3A1A:459-770
Q9Y233n/aJ2L5sh3e5sh3B1B:457-771
Q9Y233n/aJ2L5sh3e5sh3C1C:459-770
Q9Y233n/aJ2L5sh3e5sh3D1D:459-768