DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Ligand Name
(4R)-3-methyl-6-{2-[1-methyl-3-(pyrrolidin-1-yl)-1H-1,2,4-triazol-5-yl]ethyl}-2-(trifluoromethyl)imidazo[1,2-b]pyridazine
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
KVWITRNYMQYSIA-UHFFFAOYSA-N
SMILES
Cc1c(nc2n1nc(cc2)CCc3nc(nn3C)N4CCCC4)C(F)(F)F
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 5SIB
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Color Legend
Unassigned regionsLigand / hetero atomse5sibA1e5sibB1e5sibC1e5sibD1
ECOD domains from experimental PDB structures interacting with ligand JNU
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q9Y233n/aJNU5sibe5sibA1A:458-770
Q9Y233n/aJNU5sibe5sibB1B:457-771
Q9Y233n/aJNU5sibe5sibC1C:458-770
Q9Y233n/aJNU5sibe5sibD1D:458-768