DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Ligand Name
6-[(3-methylphenyl)sulfanyl]-2-[4-(pyridin-2-yl)piperazin-1-yl]-9H-purine
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
PIOPFGAPEWSFOW-UHFFFAOYSA-N
SMILES
Cc1cccc(c1)Sc2c3c([nH]cn3)nc(n2)N4CCN(CC4)c5ccccn5
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 5SIH
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Color Legend
Unassigned regionsLigand / hetero atomse5sihA1e5sihB1e5sihC1e5sihD1
ECOD domains from experimental PDB structures interacting with ligand JPF
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q9Y233n/aJPF5sihe5sihA1A:457-770
Q9Y233n/aJPF5sihe5sihB1B:457-771
Q9Y233n/aJPF5sihe5sihC1C:458-770
Q9Y233n/aJPF5sihe5sihD1D:456-768