DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Ligand Name
(4S)-5-methyl-2-{2-[1-methyl-3-(pyrrolidin-1-yl)-1H-1,2,4-triazol-5-yl]ethyl}-8-(trifluoromethyl)[1,2,4]triazolo[1,5-c]pyrimidine
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
QFPMZHXWGQCPET-UHFFFAOYSA-N
SMILES
Cc1ncc(c2n1nc(n2)CCc3nc(nn3C)N4CCCC4)C(F)(F)F
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Structure: 5SIW
Hover over the Mol* viewer to rotate or zoom with the mouse. Move the cursor out of the viewer to go back to normal page scrolling and one-click navigation.
Hover inside the viewer to rotate or zoom. Move out to scroll the page or click links normally.
Color Legend
Unassigned regionsLigand / hetero atomse5siwA1e5siwB1e5siwC1e5siwD1
ECOD domains from experimental PDB structures interacting with ligand JTX
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q9Y233n/aJTX5siwe5siwA1A:458-770
Q9Y233n/aJTX5siwe5siwB1B:457-771
Q9Y233n/aJTX5siwe5siwC1C:457-770
Q9Y233n/aJTX5siwe5siwD1D:457-768