DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Ligand Name
1-methyl-6-{2-[(4R)-1-methyl-4-phenyl-4,5-dihydro-1H-imidazol-2-yl]ethyl}-1,2,3,5-tetrahydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
YWNHEXXUQYGDSR-AWEZNQCLSA-N
SMILES
CN1CC(N=C1CCC2=NC3=C(CNN3C)C(=O)N2)c4ccccc4
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 5SJ4
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Color Legend
Unassigned regionsLigand / hetero atomse5sj4A1e5sj4B1e5sj4C1e5sj4D1
ECOD domains from experimental PDB structures interacting with ligand JXI
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q9Y233n/aJXI5sj4e5sj4A1A:458-770
Q9Y233n/aJXI5sj4e5sj4B1B:457-771
Q9Y233n/aJXI5sj4e5sj4C1C:458-770
Q9Y233n/aJXI5sj4e5sj4D1D:459-768