DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Ligand Name
3-[1-(2,5-difluorophenyl)-1H-pyrazol-5-yl]-1-[3-(trifluoromethoxy)phenyl]pyridazin-4(1H)-one
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
SXGHQUMVHHJJIH-UHFFFAOYSA-N
SMILES
c1cc(cc(c1)OC(F)(F)F)N2C=CC(=O)C(=N2)c3ccnn3c4cc(ccc4F)F
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

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Structure: 5SKD
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Color Legend
Unassigned regionsLigand / hetero atomse5skdA1e5skdB1e5skdC1e5skdD1
ECOD domains from experimental PDB structures interacting with ligand KER
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q9Y233n/aKER5skde5skdA1A:458-770
Q9Y233n/aKER5skde5skdB1B:457-771
Q9Y233n/aKER5skde5skdC1C:458-770
Q9Y233n/aKER5skde5skdD1D:456-768