DrugDomain logoDrugDomain

Attributes

UniProt ID
Protein Name
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Ligand Name
2-chloro-6-(cyclopropylamino)-N-[(4S)-2-phenyl[1,2,4]triazolo[1,5-a]pyridin-7-yl]pyridine-4-carboxamide
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
VDZMLBAIUXWXLA-UHFFFAOYSA-N
SMILES
c1ccc(cc1)c2nc3cc(ccn3n2)NC(=O)c4cc(nc(c4)Cl)NC5CC5
Drug Action
No data available
Affinity Metrics
No affinity data available

3D Structure

Interactive Mol* view for the current protein-molecule pair.

Structure: 5SKG
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Color Legend
Unassigned regionsLigand / hetero atomse5skgA1e5skgB1e5skgC1e5skgD1
ECOD domains from experimental PDB structures interacting with ligand KFI
UniProtDrugBankPDB LigandPDB IDECOD DomainRange Definition
Q9Y233n/aKFI5skge5skgA1A:458-770
Q9Y233n/aKFI5skge5skgB1B:457-771
Q9Y233n/aKFI5skge5skgC1C:458-770
Q9Y233n/aKFI5skge5skgD1D:459-768