DrugDomain

Attributes

UniProt ID

Q9Y253

Protein Name

DNA polymerase eta

Ligand Name

2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine

DrugBank ID

None

PDB Ligand Accession

XG4

ChEMBL ID

n/a

PubChem ID

n/a

InChIKey

DWGAAFQEGIMTIA-KVQBGUIXSA-N

SMILES

c1nc2c(n1C3CC(C(O3)COP(=O)(NP(=O)(O)OP(=O)(O)O)O)O)N=C(NC2=O)N

Drug Action

No data available

Affinity Metrics

No affinity data available

3D Structure

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Mol*

Structure: 3MR5

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Color Legend

Unassigned regionsLigand / hetero atomse3mr5A1e3mr5A2e3mr5A3e3mr5A4

ECOD domains from experimental PDB structures interacting with ligand XG4

UniProt	DrugBank	PDB Ligand	PDB ID	ECOD Domain	Range Definition
Q9Y253	n/a	XG4	3mr5	e3mr5A4	A:243-316
Q9Y253	n/a	XG4	3mr6	e3mr6A5	A:247-308
Q9Y253	n/a	XG4	4dl6	e4dl6A13	A:88-242
Q9Y253	n/a	XG4	4dl6	e4dl6A3	A:28-87
Q9Y253	n/a	XG4	4j9k	e4j9kA4	A:243-316
Q9Y253	n/a	XG4	4j9l	e4j9lA1	A:-2-27,A:81-242
Q9Y253	n/a	XG4	4j9l	e4j9lA3	A:28-80
Q9Y253	n/a	XG4	4j9m	e4j9mA1	A:-2-27,A:88-242
Q9Y253	n/a	XG4	4j9m	e4j9mA3	A:28-87
Q9Y253	n/a	XG4	4j9n	e4j9nA1	A:-2-27,A:88-242
Q9Y253	n/a	XG4	4j9n	e4j9nA3	A:28-87
Q9Y253	n/a	XG4	4o3q	e4o3qA1	A:-2-27,A:88-242
Q9Y253	n/a	XG4	4o3q	e4o3qA3	A:28-87
Q9Y253	n/a	XG4	4q8f	e4q8fA4	A:243-316
Q9Y253	n/a	XG4	4rnn	e4rnnA1	A:-2-27,A:88-242
Q9Y253	n/a	XG4	4rnn	e4rnnA3	A:28-87
Q9Y253	n/a	XG4	5dg9	e5dg9A3	A:28-87
Q9Y253	n/a	XG4	5dg9	e5dg9A4	A:-2-27,A:88-242
Q9Y253	n/a	XG4	5dlg	e5dlgA2	A:28-87
Q9Y253	n/a	XG4	5dlg	e5dlgA4	A:-2-27,A:88-242
Q9Y253	n/a	XG4	5dqh	e5dqhA1	A:28-87
Q9Y253	n/a	XG4	5dqh	e5dqhA3	A:-2-27,A:88-242
Q9Y253	n/a	XG4	6plc	e6plcA1	A:28-87
Q9Y253	n/a	XG4	6plc	e6plcA4	A:-2-27,A:88-242
Q9Y253	n/a	XG4	6pz3	e6pz3A1	A:28-87
Q9Y253	n/a	XG4	6pz3	e6pz3A2	A:1-27,A:88-246
Q9Y253	n/a	XG4	6uqi	e6uqiA1	A:28-87
Q9Y253	n/a	XG4	6uqi	e6uqiA2	A:-2-27,A:88-242
Q9Y253	n/a	XG4	7u7r	e7u7rA2	A:28-87
Q9Y253	n/a	XG4	7u7r	e7u7rA3	A:-2-27,A:88-242
Q9Y253	n/a	XG4	7u7s	e7u7sA3	A:28-87
Q9Y253	n/a	XG4	7u7s	e7u7sA4	A:-2-27,A:88-242
Q9Y253	n/a	XG4	7u7t	e7u7tA1	A:-2-27,A:88-242
Q9Y253	n/a	XG4	7u7t	e7u7tA3	A:28-87
Q9Y253	n/a	XG4	7u7u	e7u7uA1	A:-2-27,A:88-242
Q9Y253	n/a	XG4	7u7u	e7u7uA2	A:28-87
Q9Y253	n/a	XG4	7u7v	e7u7vA3	A:-2-27,A:88-242
Q9Y253	n/a	XG4	7u7v	e7u7vA4	A:28-87
Q9Y253	n/a	XG4	7u7w	e7u7wA1	A:28-87
Q9Y253	n/a	XG4	7u7w	e7u7wA3	A:-2-27,A:88-242
Q9Y253	n/a	XG4	7u7x	e7u7xA3	A:-2-27,A:88-242
Q9Y253	n/a	XG4	7u7x	e7u7xA4	A:28-87
Q9Y253	n/a	XG4	7u7y	e7u7yA2	A:28-87
Q9Y253	n/a	XG4	7u7y	e7u7yA3	A:-2-27,A:88-242
Q9Y253	n/a	XG4	7u7z	e7u7zA1	A:28-87
Q9Y253	n/a	XG4	7u7z	e7u7zA2	A:-2-27,A:88-242
Q9Y253	n/a	XG4	7u80	e7u80A2	A:-2-27,A:88-242
Q9Y253	n/a	XG4	7u80	e7u80A3	A:28-87
Q9Y253	n/a	XG4	7u81	e7u81A1	A:28-87
Q9Y253	n/a	XG4	7u81	e7u81A4	A:-2-27,A:88-242
Q9Y253	n/a	XG4	7u82	e7u82A2	A:28-87
Q9Y253	n/a	XG4	7u82	e7u82A4	A:-2-27,A:88-242
Q9Y253	n/a	XG4	7u83	e7u83A3	A:28-87
Q9Y253	n/a	XG4	7u83	e7u83A4	A:-2-27,A:88-242
Q9Y253	n/a	XG4	7u84	e7u84A2	A:28-87
Q9Y253	n/a	XG4	7u84	e7u84A4	A:-2-27,A:88-242
Q9Y253	n/a	XG4	8e85	e8e85A3	A:-2-27,A:88-242
Q9Y253	n/a	XG4	8e85	e8e85A4	A:28-87
Q9Y253	n/a	XG4	8e86	e8e86A2	A:-2-27,A:88-242
Q9Y253	n/a	XG4	8e86	e8e86A3	A:28-87
Q9Y253	n/a	XG4	8e87	e8e87A2	A:-2-27,A:88-242
Q9Y253	n/a	XG4	8e87	e8e87A3	A:28-87
Q9Y253	n/a	XG4	8e88	e8e88A3	A:28-87
Q9Y253	n/a	XG4	8e88	e8e88A4	A:-2-27,A:88-242
Q9Y253	n/a	XG4	8e8j	e8e8jA3	A:-2-27,A:88-242
Q9Y253	n/a	XG4	8e8j	e8e8jA4	A:28-87
Q9Y253	n/a	XG4	8e8k	e8e8kA1	A:28-87
Q9Y253	n/a	XG4	8e8k	e8e8kA4	A:-2-27,A:88-242