DrugDomain

Attributes

UniProt ID

Protein Name

Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

Ligand Name

[[(2~{R},3~{S},4~{R},5~{R})-5-[2,6-bis(oxidanylidene)-3~{H}-purin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate

DrugBank ID

None

PDB Ligand Accession

CZF

ChEMBL ID

n/a

PubChem ID

n/a

InChIKey

CAEFEWVYEZABLA-UUOKFMHZSA-N

SMILES

c1nc2c(n1C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)NC(=O)NC2=O

Drug Action

No data available

Affinity Metrics

No affinity data available

3D Structure

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Mol*

Structure: 6TX0

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Color Legend

Unassigned regionsLigand / hetero atomse6tx0A1e6tx0B1

ECOD domains from experimental PDB structures interacting with ligand CZF

UniProt	DrugBank	PDB Ligand	PDB ID	ECOD Domain	Range Definition
Q9Y3Z3	n/a	CZF	6tx0	e6tx0A1	A:114-599
Q9Y3Z3	n/a	CZF	6tx0	e6tx0B1	B:114-599
Q9Y3Z3	n/a	CZF	6txa	e6txaA1	A:114-599
Q9Y3Z3	n/a	CZF	6txa	e6txaB1	B:114-599
Q9Y3Z3	n/a	CZF	6txa	e6txaC1	C:115-599
Q9Y3Z3	n/a	CZF	6txa	e6txaD1	D:114-599
Q9Y3Z3	n/a	CZF	6txa	e6txaE1	E:114-599
Q9Y3Z3	n/a	CZF	6txa	e6txaF1	F:114-598
Q9Y3Z3	n/a	CZF	6txa	e6txaG1	G:114-598
Q9Y3Z3	n/a	CZF	6txa	e6txaH1	H:114-599
Q9Y3Z3	n/a	CZF	6txa	e6txaI1	I:115-599
Q9Y3Z3	n/a	CZF	6txa	e6txaJ1	J:115-598
Q9Y3Z3	n/a	CZF	6txa	e6txaK1	K:115-599
Q9Y3Z3	n/a	CZF	6txa	e6txaL1	L:115-600
Q9Y3Z3	n/a	CZF	6txa	e6txaM1	M:115-599
Q9Y3Z3	n/a	CZF	6txa	e6txaN1	N:115-599
Q9Y3Z3	n/a	CZF	6txa	e6txaO1	O:114-599
Q9Y3Z3	n/a	CZF	6txa	e6txaP1	P:114-598
Q9Y3Z3	n/a	CZF	6txf	e6txfA1	A:114-599
Q9Y3Z3	n/a	CZF	6txf	e6txfB1	B:114-599
Q9Y3Z3	n/a	CZF	6yom	e6yomA1	A:114-598
Q9Y3Z3	n/a	CZF	6yom	e6yomB1	B:115-598