Attributes
UniProt ID
Protein Name
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
Ligand Name
2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine
DrugBank ID
None
PDB Ligand Accession
ChEMBL ID
n/a
PubChem ID
n/a
InChIKey
WKIPJDSLGCBQCU-RRKCRQDMSA-N
SMILES
c1nc(c2c(n1)n(cn2)C3CC(C(O3)COP(=O)(NP(=O)(O)OP(=O)(O)O)O)O)N
Drug Action
No data available
Affinity Metrics
No affinity data available
3D Structure
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Structure: 6TX0
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Color Legend
Unassigned regionsLigand / hetero atomse6tx0A1e6tx0B1
ECOD domains from experimental PDB structures interacting with ligand DZ4
| UniProt | DrugBank | PDB Ligand | PDB ID | ECOD Domain | Range Definition |
|---|---|---|---|---|---|
| Q9Y3Z3 | n/a | DZ4 | 6tx0 | e6tx0A1 | A:114-599 |
| Q9Y3Z3 | n/a | DZ4 | 6tx0 | e6tx0B1 | B:114-599 |
| Q9Y3Z3 | n/a | DZ4 | 6txf | e6txfA1 | A:114-599 |
| Q9Y3Z3 | n/a | DZ4 | 6txf | e6txfB1 | B:114-599 |
| Q9Y3Z3 | n/a | DZ4 | 6xu1 | e6xu1A1 | A:113-599 |
| Q9Y3Z3 | n/a | DZ4 | 6xu1 | e6xu1B1 | B:113-598 |
| Q9Y3Z3 | n/a | DZ4 | 6xu1 | e6xu1C1 | C:113-598 |
| Q9Y3Z3 | n/a | DZ4 | 6xu1 | e6xu1D1 | D:114-598 |
| Q9Y3Z3 | n/a | DZ4 | 6xu1 | e6xu1E1 | E:113-583 |
| Q9Y3Z3 | n/a | DZ4 | 6xu1 | e6xu1F1 | F:114-600 |
| Q9Y3Z3 | n/a | DZ4 | 6xu1 | e6xu1G1 | G:114-599 |
| Q9Y3Z3 | n/a | DZ4 | 6xu1 | e6xu1H1 | H:114-598 |