DrugDomain logoDrugDomain

N-[3-[(9S)-7-azanyl-2,2-bis(fluoranyl)-9-prop-1-ynyl-6-oxa-8-azaspiro[3.5]non-7-en-9-yl]-4-fluoranyl-phenyl]-5-cyano-pyridine-2-carboxamide

Q9Y5Z0 — Beta-secretase 2

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand GX6

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand GX6

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
Q9Y5Z0n/a7d5uGX6A401e7d5uA1cradle loop barrelRIFT-relatedacid proteaseAsp
Q9Y5Z0n/a7d5uGX6A401e7d5uA2cradle loop barrelRIFT-relatedacid proteaseAsp