N-(4-tert-butylphenyl)-N-[(1R)-2-(cyclohexylamino)-2-oxo-1-(pyridin-3-yl)ethyl]-1H-imidazole-4-carboxamide
S0AP56 — ORF1ab polyprotein
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand X77
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand X77
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| S0AP56 | n/a | 6w81 | X77 | A | 401 | e6w81A1 | cradle loop barrel | RIFT-related | FMN-binding split barrel | Peptidase_C30 |
| S0AP56 | n/a | 6w81 | X77 | A | 401 | e6w81A2 | Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain | Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain | Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain | Peptidase_C30 |
| S0AP56 | n/a | 6w81 | X77 | A | 401 | e6w81B2 | cradle loop barrel | RIFT-related | FMN-binding split barrel | Peptidase_C30 |
| S0AP56 | n/a | 6w81 | X77 | B | 401 | e6w81A1 | cradle loop barrel | RIFT-related | FMN-binding split barrel | Peptidase_C30 |
| S0AP56 | n/a | 6w81 | X77 | B | 401 | e6w81B1 | Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain | Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain | Coronavirus main proteinase (3Cl-pro, putative coronavirus nsp2) C-terminal domain | Peptidase_C30 |
| S0AP56 | n/a | 6w81 | X77 | B | 401 | e6w81B2 | cradle loop barrel | RIFT-related | FMN-binding split barrel | Peptidase_C30 |