Medvedev Lab DrugDomain Protein List Small Molecules Download GitHub
Ligand name: URIDINE 5'-TRIPHOSPHATE
PDB ligand accession: UTP
DrugBank: DB04005
PubChem: 6133
ChEMBL: CHEMBL336296
InChI Key: PGAVKCOVUIYSFO-XVFCMESISA-N
SMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O

ClassyFire chemical classification:

List of proteins that are targets for DB04005

# DrugDomain Data UniProt Accession Protein name Drug Action Affinity data
1 Q586H1_UTP Q586H1 ATP synthase, epsilon n/a
2 Q4DA51_UTP Q4DA51 Uncharacterized protein n/a
3 P08518_UTP P08518 DNA-directed RNA polymerase n/a
4 Q8CBB9_UTP Q8CBB9 S-adenosylmethionine-dependent nucleotide dehydratase n/a
5 P13699_UTP P13699 Nucleoprotein (EC 3.1.13.-) n/a
6 D0EZK6_UTP D0EZK6 RNA-directed RNA polymerase n/a
7 O57934_UTP O57934 DNA primase small n/a
8 A0A161CM65_UTP A0A161CM65 ATP synthase subunit n/a
9 D3G6S4_UTP D3G6S4 UTP-monosaccharide-1-phosphate uridylyltransferase (EC n/a
10 Q9H6E5_UTP Q9H6E5 Speckle targeted PIP5K1A-regulated n/a
11 Q9VI58_UTP Q9VI58 Terminal uridylyltransferase Tailor n/a
12 Q9AGY4_UTP Q9AGY4 Glucose-1-phosphate thymidylyltransferase (EC n/a
13 Q59QT3_UTP Q59QT3 Uracil phosphoribosyltransferase n/a
14 Q4WAR0_UTP Q4WAR0 UDP-N-acetylglucosamine diphosphorylase (EC n/a
15 Q993A4_UTP Q993A4 RNA-directed RNA polymerase n/a
16 Q8RQE9_UTP Q8RQE9 DNA-directed RNA polymerase n/a
17 P29464_UTP P29464 Uridylate kinase (UK) n/a
18 P0DX98_UTP P0DX98 Cyclic dipyrimidine nucleotide n/a
19 A3DJ38_UTP A3DJ38 Metallophosphoesterase n/a
20 P71571_UTP P71571 Multifunctional non-homologous end n/a
21 G0YZJ9_UTP G0YZJ9 RNA-directed RNA polymerase n/a
22 P04050_UTP P04050 DNA-directed RNA polymerase n/a
23 Q9HUM0_UTP Q9HUM0 RNA-binding protein Hfq n/a
24 A0A7I9CFN1_UTP A0A7I9CFN1 deleted n/a
25 P33038_UTP P33038 UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC n/a
26 Q9CXY6_UTP Q9CXY6 Interleukin enhancer-binding factor n/a
27 O92972_UTP O92972 Genome polyprotein [Cleaved n/a
28 P03300_UTP P03300 Genome polyprotein [Cleaved n/a
29 Q9NP87_UTP Q9NP87 DNA-directed DNA/RNA polymerase n/a
30 Q584U8_UTP Q584U8 Uncharacterized protein n/a
31 Q0MX25_UTP Q0MX25 Polyhedrin n/a
32 P17812_UTP P17812 CTP synthase 1 n/a
33 P0A776_UTP P0A776 RNA pyrophosphohydrolase (EC n/a
34 A4UBD5_UTP A4UBD5 Terminal uridylyltransferase 4 n/a
35 Q9BZX2_UTP Q9BZX2 Uridine-cytidine kinase 2 n/a
36 Q975F9_UTP Q975F9 Bifunctional sugar-1-phosphate nucleotidylyltransferase/acetyltransferase n/a
37 A0A045IH65_UTP A0A045IH65 Uridylate kinase (UK) n/a
38 D9J2T9_UTP D9J2T9 rRNA N-glycosylase (EC n/a
39 P26663_UTP P26663 Genome polyprotein [Cleaved n/a
40 P0DTD1_UTP P0DTD1 Replicase polyprotein 1ab n/a
41 Q8RQE8_UTP Q8RQE8 DNA-directed RNA polymerase n/a
42 Q9M9P3_UTP Q9M9P3 UTP--glucose-1-phosphate uridylyltransferase 2 n/a
43 K1KYT0_UTP K1KYT0 Cyclic dipyrimidine nucleotide n/a
44 C9E870_UTP C9E870 RNA-directed RNA polymerase n/a
45 P0DSP3_UTP P0DSP3 Cyclic dipyrimidine nucleotide n/a
46 P9WHK7_UTP P9WHK7 CTP synthase (EC n/a
47 P9WPQ5_UTP P9WPQ5 Dethiobiotin synthetase BioD n/a
48 Q381M1_UTP Q381M1 Terminal uridylyltransferase 4 n/a
49 Q0QEE1_UTP Q0QEE1 Genome polyprotein n/a
50 Q9VUL1_UTP Q9VUL1 CTP synthase (EC n/a
51 P13569_UTP P13569 Cystic fibrosis transmembrane n/a
52 P9WHK5_UTP P9WHK5 Uridylate kinase (UK) n/a
53 O05338_UTP O05338 DNA primase (EC n/a
54 Q86MV5_UTP Q86MV5 Terminal uridylyltransferase 2 n/a
55 P70303_UTP P70303 CTP synthase 2 n/a
56 I3LM39_UTP I3LM39 Cyclic GMP-AMP synthase n/a
57 Q8WQX5_UTP Q8WQX5 Terminal uridylyltransferase 1 n/a
58 Q97ZE2_UTP Q97ZE2 Uridylate kinase (UK) n/a
59 P0A7F3_UTP P0A7F3 Aspartate carbamoyltransferase regulatory n/a
60 A0A6A5PYW3_UTP A0A6A5PYW3 deleted n/a
61 Q38C84_UTP Q38C84 ATPase subunit 9, n/a
62 E8Y329_UTP E8Y329 deleted n/a
63 G9MQB8_UTP G9MQB8 Radical SAM core n/a
64 P70698_UTP P70698 CTP synthase 1 n/a
65 O64642_UTP O64642 UTP:RNA uridylyltransferase 1 n/a
66 F1NBW0_UTP F1NBW0 Mitochondrial poly(A) polymerase n/a
67 P21951_UTP P21951 DNA polymerase epsilon n/a
68 P0A8V4_UTP P0A8V4 DNA-directed RNA polymerase n/a
69 X2KZJ9_UTP X2KZJ9 UTP--glucose-1-phosphate uridylyltransferase (EC n/a
70 Q02828_UTP Q02828 Genome polyprotein [Cleaved n/a
71 B1YNX3_UTP B1YNX3 UTP--glucose-1-phosphate uridylyltransferase (EC n/a
72 Q94M05_UTP Q94M05 NTPase P4 n/a
73 O13833_UTP O13833 Terminal uridylyltransferase cid1 n/a
74 Q4GZ86_UTP Q4GZ86 RNA uridylyltransferase (EC n/a
75 P0A8T7_UTP P0A8T7 DNA-directed RNA polymerase n/a
76 P49642_UTP P49642 DNA primase small n/a
77 Q9NRF8_UTP Q9NRF8 CTP synthase 2 n/a
78 Q5VYS8_UTP Q5VYS8 Terminal uridylyltransferase 7 n/a
79 O28126_UTP O28126 CCA-adding enzyme (EC n/a