DB00398
Proteins interacting with this molecule.
| DrugDomain Data | DrugBank | PDB Ligand | UniProt | Protein Name | Drug Action | Affinity |
|---|---|---|---|---|---|---|
| Explore | DB00398 | BAX | P04049 | RAF proto-oncogene serine/threonine-protein kinase | inhibitor | IC50 1 nM | Kd 230 nM |
| Explore | DB00398 | BAX | P07949 | Proto-oncogene tyrosine-protein kinase receptor Ret | inhibitor | IC50 5.9 nM | Kd 7.4 nM |
| Explore | DB00398 | BAX | P09619 | Platelet-derived growth factor receptor beta | inhibitor | IC50 0.26 nM | Kd 37 nM |
| Explore | DB00398 | BAX | P10721 | Mast/stem cell growth factor receptor Kit | antagonist | Ki 16000 nM | IC50 31 nM | Kd 16 nM |
| Explore | DB00398 | BAX | P11362 | Fibroblast growth factor receptor 1 | inhibitor | IC50 4.6 nM | Kd 2500 nM |
| Explore | DB00398 | BAX | P15056 | Serine/threonine-protein kinase B-raf | inhibitor | Ki 22 nM | IC50 4.4 nM | Kd 260 nM | EC50 3 nM |
| Explore | DB00398 | BAX | P17948 | Vascular endothelial growth factor receptor 1 | inhibitor | IC50 10 nM | Kd 31 nM |
| Explore | DB00398 | BAX | P35916 | Vascular endothelial growth factor receptor 3 | inhibitor | IC50 3 nM | Kd 16 nM |
| Explore | DB00398 | BAX | P35968 | Vascular endothelial growth factor receptor 2 | inhibitor | Ki 0.021 nM | IC50 0.06 nM | Kd 33 nM | EC50 500 nM |
| Explore | DB00398 | BAX | P36888 | Receptor-type tyrosine-protein kinase FLT3 | inhibitor | IC50 1.3 nM | Kd 4.5 nM |
| Explore | DB00398 | BAX | P49336 | Cyclin-dependent kinase 8 | no_target_action | IC50 30 nM | Kd 310 nM |
| Explore | DB00398 | BAX | Q16539 | Mitogen-activated protein kinase 14 | no_target_action | IC50 37 nM | Kd 260 nM |
Showing 12 of 12 interactions