2-((9H-PURIN-6-YLTHIO)METHYL)-5-CHLORO-3-(2-METHOXYPHENYL)QUINAZOLIN-4(3H)-ONE

O00329 — Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB06831

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
O00329	DB06831	039	nD1	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	PI3K_rbd, PI3K_p85B
O00329	DB06831	039	nD2	11.2.1	Immunoglobulin-like beta-sandwich	C2 domain	C2 domain	PI3K_C2
O00329	DB06831	039	nD3	109.4.1	Repetitive alpha hairpins	ARM repeat	ARM repeat	PI3Ka
O00329	DB06831	039	nD4	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	PI3_PI4_kinase

Show other predicted domains (50)

PDB ID	Domain Name	ECOD ID	X Group	H Group	T Group	F Group
5DXU	e5dxuA3	109.4.1	Repetitive alpha hairpins	ARM repeat	ARM repeat	14-3-3
	e5dxuA1	11.2.1	Immunoglobulin-like beta-sandwich	C2 domain	C2 domain	C2
	e5dxuA4	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e5dxuA2	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e5dxuA5	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
5M6U	e5m6uA1	109.4.1	Repetitive alpha hairpins	ARM repeat	ARM repeat	14-3-3
	e5m6uA4	11.2.1	Immunoglobulin-like beta-sandwich	C2 domain	C2 domain	C2
	e5m6uA2	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e5m6uA3	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e5m6uA5	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
5T8F	e5t8fA1	109.4.1	Repetitive alpha hairpins	ARM repeat	ARM repeat	14-3-3
	e5t8fA5	11.2.1	Immunoglobulin-like beta-sandwich	C2 domain	C2 domain	C2
	e5t8fA2	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e5t8fA3	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e5t8fA4	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
5UBT	e5ubtA5	109.4.1	Repetitive alpha hairpins	ARM repeat	ARM repeat	14-3-3
	e5ubtA3	11.2.1	Immunoglobulin-like beta-sandwich	C2 domain	C2 domain	C2
	e5ubtA2	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e5ubtA1	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e5ubtA4	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
5VLR	e5vlrA4	109.4.1	Repetitive alpha hairpins	ARM repeat	ARM repeat	14-3-3
	e5vlrA2	11.2.1	Immunoglobulin-like beta-sandwich	C2 domain	C2 domain	C2
	e5vlrA5	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e5vlrA1	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e5vlrA3	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
6G6W	e6g6wA5	109.4.1	Repetitive alpha hairpins	ARM repeat	ARM repeat	14-3-3
	e6g6wA4	11.2.1	Immunoglobulin-like beta-sandwich	C2 domain	C2 domain	C2
	e6g6wA3	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e6g6wA1	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e6g6wA2	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
6OCO	e6ocoA5	109.4.1	Repetitive alpha hairpins	ARM repeat	ARM repeat	14-3-3
	e6ocoA2	11.2.1	Immunoglobulin-like beta-sandwich	C2 domain	C2 domain	C2
	e6ocoA3	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e6ocoA1	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e6ocoA4	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
6OCU	e6ocuA1	109.4.1	Repetitive alpha hairpins	ARM repeat	ARM repeat	14-3-3
	e6ocuA3	11.2.1	Immunoglobulin-like beta-sandwich	C2 domain	C2 domain	C2
	e6ocuA5	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e6ocuA2	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e6ocuA4	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
6PYR	e6pyrA5	109.4.1	Repetitive alpha hairpins	ARM repeat	ARM repeat	14-3-3
	e6pyrA3	11.2.1	Immunoglobulin-like beta-sandwich	C2 domain	C2 domain	C2
	e6pyrA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e6pyrA2	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e6pyrA4	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
6PYU	e6pyuA5	109.4.1	Repetitive alpha hairpins	ARM repeat	ARM repeat	14-3-3
	e6pyuA3	11.2.1	Immunoglobulin-like beta-sandwich	C2 domain	C2 domain	C2
	e6pyuA1	206.1.1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
	e6pyuA2	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2
	e6pyuA4	221.1.1	beta-Grasp	Ubiquitin-related	Ubiquitin-like	Fer2

ECOD domains from experimental PDB structures interacting with ligand DB06831

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
No experimental ECOD data found