DrugDomain logoDrugDomain

6-ethyl-5-{(3R)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl}pyrimidine-2,4-diamine

Q5A5E0 — Dihydrofolate reductase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 06U

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 06U

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
Q5A5E0n/a4h9506UA202e4h95A1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
Q5A5E0n/a4h9506UB202e4h95B1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1