NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

A0A4V8GZY0 — 3-hydroxy-3-methylglutaryl coenzyme A reductase

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB03461

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB03461

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
A0A4V8GZY0	DB03461	6hr8	NAP	A	501	e6hr8A1	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
A0A4V8GZY0	DB03461	6hr8	NAP	A	501	e6hr8A2	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
A0A4V8GZY0	DB03461	6hr8	NAP	B	501	e6hr8B1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
A0A4V8GZY0	DB03461	6hr8	NAP	B	501	e6hr8B2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
A0A4V8GZY0	DB03461	6hr8	NAP	C	501	e6hr8C1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
A0A4V8GZY0	DB03461	6hr8	NAP	C	501	e6hr8C2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
A0A4V8GZY0	DB03461	6hr8	NAP	D	501	e6hr8D1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
A0A4V8GZY0	DB03461	6hr8	NAP	D	501	e6hr8D2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
A0A4V8GZY0	DB03461	6hr8	NAP	E	501	e6hr8E1	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
A0A4V8GZY0	DB03461	6hr8	NAP	E	501	e6hr8E2	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
A0A4V8GZY0	DB03461	6hr8	NAP	F	501	e6hr8F1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
A0A4V8GZY0	DB03461	6hr8	NAP	F	501	e6hr8F2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red