S-Thalidomide

A4TVL0 — Cereblon isoform 4

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand EF2

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand EF2

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
A4TVL0	n/a	4v2y	EF2	A	151	e4v2yA1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	4v2y	EF2	B	151	e4v2yB1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	4v2y	EF2	C	151	e4v2yC1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	4v32	EF2	A	151	e4v32A1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	4v32	EF2	B	151	e4v32B1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	4v32	EF2	C	151	e4v32C1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	5amh	EF2	A	151	e5amhA1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	5ami	EF2	A	151	e5amiA1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	5ami	EF2	B	151	e5amiB1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	5amj	EF2	A	151	e5amjA1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	5amj	EF2	B	151	e5amjB1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	5amk	EF2	A	151	e5amkA1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	5amk	EF2	B	151	e5amkB1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	5amk	EF2	B	151	e5amkD1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	5oh1	EF2	A	202	e5oh1A1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	5oh1	EF2	B	202	e5oh1B1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	6r0s	EF2	A	202	e6r0sA1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	6r0s	EF2	A	202	e6r0sC1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	6r0u	EF2	A	202	e6r0uA1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	6r12	EF2	A	202	e6r12A1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	6r12	EF2	A	202	e6r12C1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	6r12	EF2	C	202	e6r12C1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	6r13	EF2	A	202	e6r13A1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	6r18	EF2	A	202	e6r18A1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	6r18	EF2	C	202	e6r18C1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	6r19	EF2	A	202	e6r19A1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	6r19	EF2	A	202	e6r19C1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	6r19	EF2	C	202	e6r19C1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	6r1a	EF2	A	202	e6r1aA1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	6r1a	EF2	A	202	e6r1aC1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	6r1a	EF2	B	202	e6r1aB1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	6r1c	EF2	A	203	e6r1cA1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	6r1c	EF2	A	203	e6r1cC1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	6r1c	EF2	C	202	e6r1cC1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	6r1w	EF2	A	202	e6r1wA1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	6r1w	EF2	A	202	e6r1wC1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	7pso	EF2	A	202	e7psoA1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	7pso	EF2	B	202	e7psoB1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	8bc7	EF2	A	202	e8bc7A1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	8bc7	EF2	C	202	e8bc7C1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	Yippee-Mis18
A4TVL0	n/a	8ou3	EF2	A	202	e8ou3A1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	RIG-I_C-RD
A4TVL0	n/a	8ou3	EF2	C	202	e8ou3C1	ETN0001 domain-like	ETN0001 domain-like	Mss4-like	RIG-I_C-RD