[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-[[(2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-3-hydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-3-hydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate

A5H025 — Ribonuclease L

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 25L

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 25L

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
A5H025	n/a	4o1o	25L	A	1000	e4o1oA3	Repetitive alpha hairpins	Ankyrin repeat	Ankyrin repeat	Ank_2
A5H025	n/a	4o1o	25L	A	1000	e4o1oB2	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
A5H025	n/a	4o1o	25L	A	1000	e4o1oB3	Repetitive alpha hairpins	Ankyrin repeat	Ankyrin repeat	Ank_2
A5H025	n/a	4o1o	25L	B	1000	e4o1oA2	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
A5H025	n/a	4o1o	25L	B	1000	e4o1oA3	Repetitive alpha hairpins	Ankyrin repeat	Ankyrin repeat	Ank_2
A5H025	n/a	4o1o	25L	B	1000	e4o1oB3	Repetitive alpha hairpins	Ankyrin repeat	Ankyrin repeat	Ank_2
A5H025	n/a	4o1o	25L	C	1000	e4o1oC3	Repetitive alpha hairpins	Ankyrin repeat	Ankyrin repeat	Ank_2
A5H025	n/a	4o1o	25L	C	1000	e4o1oD2	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
A5H025	n/a	4o1o	25L	C	1000	e4o1oD3	Repetitive alpha hairpins	Ankyrin repeat	Ankyrin repeat	Ank_2
A5H025	n/a	4o1o	25L	D	1000	e4o1oC2	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
A5H025	n/a	4o1o	25L	D	1000	e4o1oC3	Repetitive alpha hairpins	Ankyrin repeat	Ankyrin repeat	Ank_2
A5H025	n/a	4o1o	25L	D	1000	e4o1oD3	Repetitive alpha hairpins	Ankyrin repeat	Ankyrin repeat	Ank_2
A5H025	n/a	4o1p	25L	A	904	e4o1pA3	Repetitive alpha hairpins	Ankyrin repeat	Ankyrin repeat	Ank_2
A5H025	n/a	4o1p	25L	A	904	e4o1pB2	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
A5H025	n/a	4o1p	25L	A	904	e4o1pB3	Repetitive alpha hairpins	Ankyrin repeat	Ankyrin repeat	Ank_2
A5H025	n/a	4o1p	25L	B	904	e4o1pA2	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
A5H025	n/a	4o1p	25L	B	904	e4o1pA3	Repetitive alpha hairpins	Ankyrin repeat	Ankyrin repeat	Ank_2
A5H025	n/a	4o1p	25L	B	904	e4o1pB3	Repetitive alpha hairpins	Ankyrin repeat	Ankyrin repeat	Ank_2
A5H025	n/a	4o1p	25L	C	904	e4o1pC1	Repetitive alpha hairpins	Ankyrin repeat	Ankyrin repeat	Ank_2
A5H025	n/a	4o1p	25L	C	904	e4o1pD2	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
A5H025	n/a	4o1p	25L	C	904	e4o1pD3	Repetitive alpha hairpins	Ankyrin repeat	Ankyrin repeat	Ank_2
A5H025	n/a	4o1p	25L	D	904	e4o1pC1	Repetitive alpha hairpins	Ankyrin repeat	Ankyrin repeat	Ank_2
A5H025	n/a	4o1p	25L	D	904	e4o1pC2	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
A5H025	n/a	4o1p	25L	D	904	e4o1pD3	Repetitive alpha hairpins	Ankyrin repeat	Ankyrin repeat	Ank_2
A5H025	n/a	6m12	25L	a	802	e6m12a2	Repetitive alpha hairpins	Ankyrin repeat	Ankyrin repeat	Ank_2
A5H025	n/a	6m12	25L	a	802	e6m12b2	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
A5H025	n/a	6m12	25L	a	802	e6m12b3	Repetitive alpha hairpins	Ankyrin repeat	Ankyrin repeat	Ank_2
A5H025	n/a	6m12	25L	b	801	e6m12a1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
A5H025	n/a	6m12	25L	b	801	e6m12a2	Repetitive alpha hairpins	Ankyrin repeat	Ankyrin repeat	Ank_2
A5H025	n/a	6m12	25L	b	801	e6m12b3	Repetitive alpha hairpins	Ankyrin repeat	Ankyrin repeat	Ank_2
A5H025	n/a	6m13	25L	a	802	e6m13a2	Repetitive alpha hairpins	Ankyrin repeat	Ankyrin repeat	Ank_2
A5H025	n/a	6m13	25L	a	802	e6m13b1	Repetitive alpha hairpins	Ankyrin repeat	Ankyrin repeat	Ank_2
A5H025	n/a	6m13	25L	a	802	e6m13b2	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
A5H025	n/a	6m13	25L	b	902	e6m13a2	Repetitive alpha hairpins	Ankyrin repeat	Ankyrin repeat	Ank_2
A5H025	n/a	6m13	25L	b	902	e6m13a3	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
A5H025	n/a	6m13	25L	b	902	e6m13b1	Repetitive alpha hairpins	Ankyrin repeat	Ankyrin repeat	Ank_2
A5H025	n/a	7elw	25L	a	801	e7elwa1	Repetitive alpha hairpins	Ankyrin repeat	Ankyrin repeat	Ank_2
A5H025	n/a	7elw	25L	a	801	e7elwb1	Repetitive alpha hairpins	Ankyrin repeat	Ankyrin repeat	Ank_2
A5H025	n/a	7elw	25L	a	801	e7elwb2	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
A5H025	n/a	7elw	25L	b	801	e7elwa1	Repetitive alpha hairpins	Ankyrin repeat	Ankyrin repeat	Ank_2
A5H025	n/a	7elw	25L	b	801	e7elwa2	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	Pkinase
A5H025	n/a	7elw	25L	b	801	e7elwb1	Repetitive alpha hairpins	Ankyrin repeat	Ankyrin repeat	Ank_2