2-OXOGLUTARIC ACID

O75874 — Isocitrate dehydrogenase cytoplasmic -specific ICDH

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB08845

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB08845

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
O75874	DB08845	3inm	AKG	A	511	e3inmA1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	3inm	AKG	A	511	e3inmA2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	3inm	AKG	A	511	e3inmB1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	3inm	AKG	B	511	e3inmA1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	3inm	AKG	B	511	e3inmA2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	3inm	AKG	B	511	e3inmB1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	3inm	AKG	B	511	e3inmB2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	3inm	AKG	C	511	e3inmC1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	3inm	AKG	C	511	e3inmC2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4kzo	AKG	A	503	e4kzoA1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4kzo	AKG	A	503	e4kzoA2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4kzo	AKG	A	503	e4kzoB2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4kzo	AKG	B	503	e4kzoA1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4kzo	AKG	B	503	e4kzoA2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4kzo	AKG	B	503	e4kzoB1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4kzo	AKG	B	503	e4kzoB2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4kzo	AKG	C	503	e4kzoC1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4kzo	AKG	C	503	e4kzoC2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l03	AKG	A	504	e4l03A1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l03	AKG	A	504	e4l03A2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l03	AKG	A	504	e4l03B1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l03	AKG	B	503	e4l03A1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l03	AKG	B	503	e4l03A2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l03	AKG	B	503	e4l03B1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l03	AKG	B	503	e4l03B2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l03	AKG	C	503	e4l03C1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l03	AKG	C	503	e4l03C2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l04	AKG	A	501	e4l04A1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l04	AKG	A	501	e4l04A2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l04	AKG	A	501	e4l04B2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l04	AKG	B	501	e4l04A1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l04	AKG	B	501	e4l04A2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l04	AKG	B	501	e4l04B1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l04	AKG	B	501	e4l04B2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l04	AKG	C	501	e4l04C1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l04	AKG	C	501	e4l04C2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l04	AKG	C	501	e4l04D1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l04	AKG	D	501	e4l04C1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l04	AKG	D	501	e4l04D1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l04	AKG	D	501	e4l04D2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l04	AKG	E	501	e4l04E1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l04	AKG	E	501	e4l04E2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l04	AKG	E	501	e4l04F1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l04	AKG	F	501	e4l04E2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l04	AKG	F	501	e4l04F1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l04	AKG	F	501	e4l04F2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l06	AKG	A	503	e4l06A1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l06	AKG	A	503	e4l06A2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l06	AKG	A	503	e4l06B1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l06	AKG	B	503	e4l06A1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l06	AKG	B	503	e4l06A2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l06	AKG	B	503	e4l06B1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l06	AKG	B	503	e4l06B2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l06	AKG	C	503	e4l06C1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l06	AKG	C	503	e4l06C2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l06	AKG	C	503	e4l06D1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l06	AKG	D	503	e4l06C1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l06	AKG	D	503	e4l06D1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l06	AKG	D	503	e4l06D2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l06	AKG	E	503	e4l06E1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l06	AKG	E	503	e4l06E2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l06	AKG	E	503	e4l06F2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l06	AKG	F	503	e4l06E1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l06	AKG	F	503	e4l06F1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	4l06	AKG	F	503	e4l06F2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	7pjm	AKG	A	501	e7pjmA1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	7pjm	AKG	A	501	e7pjmA2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	7pjm	AKG	A	501	e7pjmB1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	7pjm	AKG	B	502	e7pjmA1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	7pjm	AKG	B	502	e7pjmA2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	7pjm	AKG	B	502	e7pjmB1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	7pjm	AKG	B	502	e7pjmB2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	7pjm	AKG	C	1203	e7pjmC1	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh
O75874	DB08845	7pjm	AKG	C	1203	e7pjmC2	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Iso_dh