DrugDomain logoDrugDomain

2-{3-[3-(cyclopentylethynyl)-4-fluorophenyl]-5-(cyclopropylmethyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]-1H-pyrazol-1-yl}-1,3-thiazole-4-carboxylic acid

P00338 — L-lactate dehydrogenase A chain

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand P8M

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand P8M

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P00338n/a6q0dP8MA502e6q0dA1LDH C-terminal domain-likeLDH C-terminal domain-likeLDH C-terminal domain-likeLdh_1_C
P00338n/a6q0dP8MA502e6q0dA2Rossmann-likeRossmann-relatedNAD(P)-binding Rossmann-fold domainsLdh_1_N
P00338n/a6q0dP8MB502e6q0dB1Rossmann-likeRossmann-relatedNAD(P)-binding Rossmann-fold domainsLdh_1_N
P00338n/a6q0dP8MB502e6q0dB2LDH C-terminal domain-likeLDH C-terminal domain-likeLDH C-terminal domain-likeLdh_1_C
P00338n/a6q0dP8MC502e6q0dC1LDH C-terminal domain-likeLDH C-terminal domain-likeLDH C-terminal domain-likeLdh_1_C
P00338n/a6q0dP8MC502e6q0dC2Rossmann-likeRossmann-relatedNAD(P)-binding Rossmann-fold domainsLdh_1_N
P00338n/a6q0dP8MD502e6q0dD1LDH C-terminal domain-likeLDH C-terminal domain-likeLDH C-terminal domain-likeLdh_1_C
P00338n/a6q0dP8MD502e6q0dD2Rossmann-likeRossmann-relatedNAD(P)-binding Rossmann-fold domainsLdh_1_N
P00338n/a6q0dP8ME405e6q0dE1Rossmann-likeRossmann-relatedNAD(P)-binding Rossmann-fold domainsLdh_1_N
P00338n/a6q0dP8ME405e6q0dE2LDH C-terminal domain-likeLDH C-terminal domain-likeLDH C-terminal domain-likeLdh_1_C
P00338n/a6q0dP8MF502e6q0dF1LDH C-terminal domain-likeLDH C-terminal domain-likeLDH C-terminal domain-likeLdh_1_C
P00338n/a6q0dP8MF502e6q0dF2Rossmann-likeRossmann-relatedNAD(P)-binding Rossmann-fold domainsLdh_1_N