DrugDomain logoDrugDomain

6-ethyl-5-{(3R)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl}pyrimidine-2,4-diamine

P00374 — Dihydrofolate reductase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 06U

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 06U

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P00374n/a4kak06UA202e4kakA1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
P00374n/a4kak06UB202e4kakB1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1