DrugDomain logoDrugDomain

6-ethyl-5-{3-[3-(pyrimidin-5-yl)phenyl]prop-1-yn-1-yl}pyrimidine-2,4-diamine

P00374 — Dihydrofolate reductase

← Back

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 25U

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 25U

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P00374n/a4kbn25UA201e4kbnA1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
P00374n/a4kbn25UB202e4kbnB1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1