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5-[(1E)-2-(2-methoxyphenyl)-4-methylpent-1-en-1-yl]furo[2,3-d]pyrimidine-2,4-diamine

P00374 — Dihydrofolate reductase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand D2D

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand D2D

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P00374n/a3nxrD2DA192e3nxrA1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
P00374n/a3nxxD2DA189e3nxxA1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1