DrugDomain logoDrugDomain

3'-[(2R)-4-(2,4-diamino-6-ethylpyrimidin-5-yl)but-3-yn-2-yl]-5'-methoxy[1,1'-biphenyl]-4-carboxylic acid

P00374 — Dihydrofolate reductase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand G6Y

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand G6Y

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P00374n/a6de4G6YA202e6de4A1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
P00374n/a6de4G6YB202e6de4B1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1