6-{[(2,5-dichlorophenyl)amino]methyl}pyrido[2,3-d]pyrimidine-2,4-diamine
P00374 — Dihydrofolate reductase
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand OAG
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand OAG
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| P00374 | n/a | 3l3r | OAG | A | 187 | e3l3rA1 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| P00374 | n/a | 3oaf | OAG | A | 187 | e3oafA1 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| P00374 | n/a | 4g95 | OAG | A | 201 | e4g95A1 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |