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TRIMETHOPRIM

P00374 — Dihydrofolate reductase

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Attributes

UniProt ID
P00374
Protein Name
Dihydrofolate reductase
Ligand Name
TRIMETHOPRIM
DrugBank ID
DB00440
PDB Ligand Accession
TOP
ChEMBL ID
CHEMBL22
PubChem ID
5578
InChIKey
IEDVJHCEMCRBQM-UHFFFAOYSA-N
SMILES
COc1cc(cc(c1OC)OC)Cc2cnc(nc2N)N
Drug Action
modulator
Affinity Metrics
ki:0.006 nM
ic50:27 nM