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6-{[(2,5-DIETHOXYPHENYL)AMINO]METHYL}-5-METHYLPYRIDO[2,3-D]PYRIMIDINE-2,4-DIAMINE

P00374 — Dihydrofolate reductase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand VG9

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand VG9

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P00374n/a2w3bVG9A301e2w3bA1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
P00374n/a2w3bVG9B301e2w3bB1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1