(3R,5R)-7-[5-(ANILINOCARBONYL)-3,4-BIS(4-FLUOROPHENYL)-1-ISOPROPYL-1H-PYRROL-2-YL]-3,5-DIHYDROXYHEPTANOIC ACID

P04035 — 3-hydroxy-3-methylglutaryl-coenzyme A reductase

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 882

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 882

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P04035	n/a	2q1l	882	A	877	e2q1lA1	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	n/a	2q1l	882	A	877	e2q1lA2	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	n/a	2q1l	882	A	877	e2q1lB2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	n/a	2q1l	882	C	876	e2q1lC1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	n/a	2q1l	882	C	876	e2q1lD2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	n/a	2q1l	882	D	876	e2q1lC2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	n/a	2q1l	882	D	876	e2q1lD1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	n/a	2q1l	882	D	876	e2q1lD2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	n/a	3cd7	882	A	2	e3cd7A1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	n/a	3cd7	882	A	2	e3cd7A2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	n/a	3cd7	882	A	2	e3cd7B2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	n/a	3cd7	882	C	4	e3cd7C1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	n/a	3cd7	882	C	4	e3cd7D2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	n/a	3cd7	882	D	3	e3cd7C2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	n/a	3cd7	882	D	3	e3cd7D1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	n/a	3cd7	882	D	3	e3cd7D2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red