ADENOSINE-5'-DIPHOSPHATE

P04035 — 3-hydroxy-3-methylglutaryl-coenzyme A reductase

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB16833

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB16833

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P04035	DB16833	1hw8	ADP	B	101	e1hw8A2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hw8	ADP	B	101	e1hw8B2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hw8	ADP	D	102	e1hw8D1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hw8	ADP	D	102	e1hw8D2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hw9	ADP	A	102	e1hw9A2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hw9	ADP	A	102	e1hw9B2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hw9	ADP	B	104	e1hw9B1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hw9	ADP	B	104	e1hw9B2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hw9	ADP	C	103	e1hw9C2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hw9	ADP	C	103	e1hw9D2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hw9	ADP	D	105	e1hw9D1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hw9	ADP	D	105	e1hw9D2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hwi	ADP	B	102	e1hwiB1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hwi	ADP	B	102	e1hwiB2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hwi	ADP	D	103	e1hwiD1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hwi	ADP	D	103	e1hwiD2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hwj	ADP	A	102	e1hwjA2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hwj	ADP	A	102	e1hwjB2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hwj	ADP	B	105	e1hwjB1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hwj	ADP	B	105	e1hwjB2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hwj	ADP	C	104	e1hwjC1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hwj	ADP	C	104	e1hwjC2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hwj	ADP	D	106	e1hwjD1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hwj	ADP	D	106	e1hwjD2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hwk	ADP	A	103	e1hwkA1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hwk	ADP	A	103	e1hwkA2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hwk	ADP	B	104	e1hwkB1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hwk	ADP	B	104	e1hwkB2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hwk	ADP	D	105	e1hwkD1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hwk	ADP	D	105	e1hwkD2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hwl	ADP	A	102	e1hwlA2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hwl	ADP	A	102	e1hwlB2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hwl	ADP	C	103	e1hwlC2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB16833	1hwl	ADP	C	103	e1hwlD2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red