3-HYDROXY-3-METHYL-GLUTARIC ACID

P04035 — 3-hydroxy-3-methylglutaryl-coenzyme A reductase

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB04377

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB04377

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P04035	DB04377	1dq8	MAH	A	200	e1dq8A2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB04377	1dq8	MAH	A	200	e1dq8B1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB04377	1dq8	MAH	A	200	e1dq8B2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB04377	1dq8	MAH	B	201	e1dq8A1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB04377	1dq8	MAH	B	201	e1dq8A2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB04377	1dq8	MAH	B	201	e1dq8B2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB04377	1dq8	MAH	D	203	e1dq8C1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB04377	1dq8	MAH	D	203	e1dq8C2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB04377	1dq8	MAH	D	203	e1dq8D2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB04377	1dqa	MAH	A	201	e1dqaA2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB04377	1dqa	MAH	A	201	e1dqaB1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB04377	1dqa	MAH	A	201	e1dqaB2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB04377	1dqa	MAH	B	202	e1dqaA1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB04377	1dqa	MAH	B	202	e1dqaA2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB04377	1dqa	MAH	B	202	e1dqaB2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB04377	1dqa	MAH	C	204	e1dqaC1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB04377	1dqa	MAH	C	204	e1dqaC2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB04377	1dqa	MAH	C	204	e1dqaD2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB04377	1dqa	MAH	D	203	e1dqaC2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB04377	1dqa	MAH	D	203	e1dqaD1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P04035	DB04377	1dqa	MAH	D	203	e1dqaD2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red