4-[[3-chloro-4-(1-methylimidazol-2-yl)sulfanyl-phenyl]amino]-7-[3-(2-hydroxyethyl-methyl-amino)propoxy]-6-methoxy-quinoline-3-carbonitrile

P08069 — Insulin-like growth factor 1 receptor

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 741

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 741

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P08069	n/a	3f5p	741	A	1	e3f5pA1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	PK_Tyr_Ser-Thr
P08069	n/a	3f5p	741	B	2	e3f5pB1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	PK_Tyr_Ser-Thr
P08069	n/a	3f5p	741	C	3	e3f5pC1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	PK_Tyr_Ser-Thr
P08069	n/a	3f5p	741	D	4	e3f5pD1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	PK_Tyr_Ser-Thr
P08069	n/a	3f5p	741	E	5	e3f5pE1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	PK_Tyr_Ser-Thr
P08069	n/a	3f5p	741	F	6	e3f5pF1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	PK_Tyr_Ser-Thr
P08069	n/a	3f5p	741	G	7	e3f5pG1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	PK_Tyr_Ser-Thr
P08069	n/a	3f5p	741	H	8	e3f5pH1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	PK_Tyr_Ser-Thr
P08069	n/a	3f5p	741	I	9	e3f5pI1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	PK_Tyr_Ser-Thr
P08069	n/a	3f5p	741	J	10	e3f5pJ1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	PK_Tyr_Ser-Thr
P08069	n/a	3f5p	741	K	11	e3f5pK1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	PK_Tyr_Ser-Thr
P08069	n/a	3f5p	741	L	13	e3f5pL1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	PK_Tyr_Ser-Thr
P08069	n/a	3f5p	741	M	12	e3f5pM1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	PK_Tyr_Ser-Thr
P08069	n/a	3f5p	741	R	14	e3f5pR1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	PK_Tyr_Ser-Thr
P08069	n/a	3f5p	741	S	15	e3f5pS1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	PK_Tyr_Ser-Thr
P08069	n/a	3f5p	741	T	16	e3f5pT1	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase/SAICAR synthase/ATP-grasp	Protein kinase	PK_Tyr_Ser-Thr