DrugDomain logoDrugDomain

6-ethyl-5-{(3R)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl}pyrimidine-2,4-diamine

P0A017 Dihydrofolate reductase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 06U

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 06U

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P0A017n/a4xe606UX201e4xe6X1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
P0A017n/a4xec06UX201e4xecX1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
P0A017n/a7t7q06UX202e7t7qX1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
P0A017n/a7t7s06UX202e7t7sX1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1