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6-ethyl-5-[3-(4-methoxybiphenyl-3-yl)prop-1-yn-1-yl]pyrimidine-2,4-diamine

P0A017 — Dihydrofolate reductase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 5DR

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 5DR

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P0A017n/a3sh25DRA168e3sh2A1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
P0A017n/a3sh25DRB168e3sh2B1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1