DrugDomain logoDrugDomain

4-[3-[3-[2,4-bis(azanyl)-6-ethyl-pyrimidin-5-yl]prop-2-ynyl]-4-methoxy-phenyl]benzoic acid

P0A017 Dihydrofolate reductase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand U06

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand U06

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P0A017n/a5hf0U06X202e5hf0X1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
P0A017n/a5ispU06X202e5ispX1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
P0A017n/a5isqU06X202e5isqX1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
P0A017n/a5istU06X201e5istX1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1