3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-2-{(1S)-1-HYDROXY-1-[(R)-HYDROXY(METHOXY)PHOSPHORYL]ETHYL}-5-(2-{[(S)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}ETHYL)-4-METHYL-1,3-THIAZOL-3-IUM

P0AEP7 — Glyoxylate carboligase

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand TDK

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand TDK

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P0AEP7	n/a	8beo	TDK	A	604	e8beoA1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_C
P0AEP7	n/a	8beo	TDK	A	604	e8beoA2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
P0AEP7	n/a	8beo	TDK	A	604	e8beoA3	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_N
P0AEP7	n/a	8beo	TDK	B	604	e8beoB1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_N
P0AEP7	n/a	8beo	TDK	B	604	e8beoB2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
P0AEP7	n/a	8beo	TDK	B	604	e8beoB3	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_C
P0AEP7	n/a	8beo	TDK	C	603	e8beoC1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
P0AEP7	n/a	8beo	TDK	C	603	e8beoC2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_N
P0AEP7	n/a	8beo	TDK	C	603	e8beoC3	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_C
P0AEP7	n/a	8beo	TDK	C	603	e8beoE1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_N
P0AEP7	n/a	8beo	TDK	C	603	e8beoE2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_C
P0AEP7	n/a	8beo	TDK	D	603	e8beoD1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_N
P0AEP7	n/a	8beo	TDK	D	603	e8beoD2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_C
P0AEP7	n/a	8beo	TDK	D	603	e8beoD3	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
P0AEP7	n/a	8beo	TDK	D	603	e8beoF1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_N
P0AEP7	n/a	8beo	TDK	E	603	e8beoC2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_N
P0AEP7	n/a	8beo	TDK	E	603	e8beoE1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_N
P0AEP7	n/a	8beo	TDK	E	603	e8beoE2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_C
P0AEP7	n/a	8beo	TDK	E	603	e8beoE3	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M
P0AEP7	n/a	8beo	TDK	F	604	e8beoD1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_N
P0AEP7	n/a	8beo	TDK	F	604	e8beoF1	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_N
P0AEP7	n/a	8beo	TDK	F	604	e8beoF2	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	TPP_enzyme_C
P0AEP7	n/a	8beo	TDK	F	604	e8beoF3	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	TPP_enzyme_M