Memantine

P0C7B7 — Cys-loop ligand-gated ion channel

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 377

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 377

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P0C7B7	n/a	4twd	377	A	402	e4twdA1	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neur_chan_memb
P0C7B7	n/a	4twd	377	A	402	e4twdB1	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neur_chan_memb
P0C7B7	n/a	4twd	377	A	402	e4twdC1	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neur_chan_memb
P0C7B7	n/a	4twd	377	A	402	e4twdD1	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neur_chan_memb
P0C7B7	n/a	4twd	377	A	402	e4twdE1	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neur_chan_memb
P0C7B7	n/a	4twd	377	B	401	e4twdA2	Immunoglobulin-like beta-sandwich	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Neur_chan_LBD
P0C7B7	n/a	4twd	377	B	401	e4twdB2	Immunoglobulin-like beta-sandwich	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Neur_chan_LBD
P0C7B7	n/a	4twd	377	C	402	e4twdC2	Immunoglobulin-like beta-sandwich	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Neur_chan_LBD
P0C7B7	n/a	4twd	377	C	402	e4twdD2	Immunoglobulin-like beta-sandwich	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Neur_chan_LBD
P0C7B7	n/a	4twd	377	E	401	e4twdD2	Immunoglobulin-like beta-sandwich	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Neur_chan_LBD
P0C7B7	n/a	4twd	377	E	401	e4twdE2	Immunoglobulin-like beta-sandwich	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Neur_chan_LBD
P0C7B7	n/a	4twd	377	F	402	e4twdF1	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neur_chan_memb
P0C7B7	n/a	4twd	377	F	402	e4twdG1	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neur_chan_memb
P0C7B7	n/a	4twd	377	F	402	e4twdH1	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neur_chan_memb
P0C7B7	n/a	4twd	377	F	402	e4twdI1	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neur_chan_memb
P0C7B7	n/a	4twd	377	F	402	e4twdJ1	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neurotransmitter-gated ion-channel transmembrane pore	Neur_chan_memb
P0C7B7	n/a	4twd	377	G	401	e4twdF2	Immunoglobulin-like beta-sandwich	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Neur_chan_LBD
P0C7B7	n/a	4twd	377	G	401	e4twdG2	Immunoglobulin-like beta-sandwich	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Neur_chan_LBD
P0C7B7	n/a	4twd	377	H	402	e4twdH2	Immunoglobulin-like beta-sandwich	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Neur_chan_LBD
P0C7B7	n/a	4twd	377	H	402	e4twdI2	Immunoglobulin-like beta-sandwich	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Neur_chan_LBD
P0C7B7	n/a	4twd	377	J	401	e4twdI2	Immunoglobulin-like beta-sandwich	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Neur_chan_LBD
P0C7B7	n/a	4twd	377	J	401	e4twdJ2	Immunoglobulin-like beta-sandwich	Nicotinic receptor ligand binding domain-like	Nicotinic receptor ligand binding domain-like	Neur_chan_LBD