(S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE

P11387 — DNA topoisomerase 1

ECOD Domain Annotations

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P11387	DB01030	1k4t	TTC	D	990	e1k4tA1	Beta-strand domain in eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	Beta-strand domain in eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	Beta-strand domain in eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	Topoisom_I_N
P11387	DB01030	1k4t	TTC	D	990	e1k4tA2	HTH	HTH	DNA breaking-rejoining enzymes	Topoisom_I
P11387	DB01030	1k4t	TTC	D	990	e1k4tA3	HTH	HTH	DNA breaking-rejoining enzymes	Topoisom_I,Topo_C_assoc
P11387	DB01030	1rr8	TTC	A	100	e1rr8C5	HTH	HTH	DNA breaking-rejoining enzymes	Topoisom_I
P11387	DB01030	1rr8	TTC	A	100	e1rr8C6	HTH	HTH	DNA breaking-rejoining enzymes	Topo_C_assoc
P11387	DB01030	1rr8	TTC	A	100	e1rr8C8	Beta-strand domain in eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	Beta-strand domain in eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	Beta-strand domain in eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	Topoisom_I_N
P11387	DB01030	1rrj	TTC	B	990	e1rrjA1	Beta-strand domain in eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	Beta-strand domain in eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	Beta-strand domain in eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	Topoisom_I_N
P11387	DB01030	1rrj	TTC	B	990	e1rrjA2	HTH	HTH	DNA breaking-rejoining enzymes	Topoisom_I
P11387	DB01030	1rrj	TTC	B	990	e1rrjA3	HTH	HTH	DNA breaking-rejoining enzymes	Topoisom_I,Topo_C_assoc