(R)-MEVALONATE

P13702 — 3-hydroxy-3-methylglutaryl-coenzyme A reductase

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB03518

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB03518

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P13702	DB03518	1qay	MEV	A	1002	e1qayA2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P13702	DB03518	1qay	MEV	A	1002	e1qayB1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P13702	DB03518	1r31	MEV	A	1003	e1r31A2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P13702	DB03518	1r31	MEV	A	1003	e1r31B1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P13702	DB03518	1r31	MEV	A	1003	e1r31B2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P13702	DB03518	1r31	MEV	B	1004	e1r31A1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P13702	DB03518	1r31	MEV	B	1004	e1r31A2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P13702	DB03518	1r31	MEV	B	1004	e1r31B2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P13702	DB03518	4i6y	MEV	A	501	e4i6yA2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P13702	DB03518	4i6y	MEV	A	501	e4i6yB1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P13702	DB03518	4i6y	MEV	A	501	e4i6yB2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P13702	DB03518	4i6y	MEV	B	1001	e4i6yA1	Alpha-beta plaits	HMG-CoA reductase	NAD-binding domain of HMG-CoA reductase	HMG-CoA_red
P13702	DB03518	4i6y	MEV	B	1001	e4i6yA2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red
P13702	DB03518	4i6y	MEV	B	1001	e4i6yB2	Alpha-beta plaits	HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	HMG-CoA_red