(4~{S},11~{S},18~{S})-4,11-dimethyl-18-(sulfanylmethyl)-6,13,20-trithia-3,10,17,22,23,24-hexazatetracyclo[17.2.1.1^{5,8}.1^{12,15}]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione

P21447 — ATP-dependent translocase ABCB1

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand JIZ

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand JIZ

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
P21447	n/a	7zk5	JIZ	A	2010	e7zk5A2	Type II ABC exporter transmembrane domain fold	Type I ABC exporter transmembrane domain fold	Type I ABC exporter transmembrane domain fold	ABC_membrane
P21447	n/a	7zk5	JIZ	A	2010	e7zk5A4	Type II ABC exporter transmembrane domain fold	Type I ABC exporter transmembrane domain fold	Type I ABC exporter transmembrane domain fold	ABC_membrane
P21447	n/a	7zk6	JIZ	A	2007	e7zk6A1	Type II ABC exporter transmembrane domain fold	Type I ABC exporter transmembrane domain fold	Type I ABC exporter transmembrane domain fold	ABC_membrane
P21447	n/a	7zk6	JIZ	A	2007	e7zk6A2	Type II ABC exporter transmembrane domain fold	Type I ABC exporter transmembrane domain fold	Type I ABC exporter transmembrane domain fold	ABC_membrane
P21447	n/a	7zk8	JIZ	A	2005	e7zk8A1	Type II ABC exporter transmembrane domain fold	Type I ABC exporter transmembrane domain fold	Type I ABC exporter transmembrane domain fold	ABC_membrane
P21447	n/a	7zk8	JIZ	A	2005	e7zk8A4	Type II ABC exporter transmembrane domain fold	Type I ABC exporter transmembrane domain fold	Type I ABC exporter transmembrane domain fold	ABC_membrane
P21447	n/a	7zk9	JIZ	A	1301	e7zk9A1	Type II ABC exporter transmembrane domain fold	Type I ABC exporter transmembrane domain fold	Type I ABC exporter transmembrane domain fold	ABC_membrane
P21447	n/a	7zk9	JIZ	A	1301	e7zk9A3	Type II ABC exporter transmembrane domain fold	Type I ABC exporter transmembrane domain fold	Type I ABC exporter transmembrane domain fold	ABC_membrane
P21447	n/a	7zka	JIZ	A	1401	e7zkaA2	Type II ABC exporter transmembrane domain fold	Type I ABC exporter transmembrane domain fold	Type I ABC exporter transmembrane domain fold	ABC_membrane
P21447	n/a	7zka	JIZ	A	1401	e7zkaA4	Type II ABC exporter transmembrane domain fold	Type I ABC exporter transmembrane domain fold	Type I ABC exporter transmembrane domain fold	ABC_membrane
P21447	n/a	7zkb	JIZ	A	1401	e7zkbA1	Type II ABC exporter transmembrane domain fold	Type I ABC exporter transmembrane domain fold	Type I ABC exporter transmembrane domain fold	ABC_membrane
P21447	n/a	7zkb	JIZ	A	1401	e7zkbA4	Type II ABC exporter transmembrane domain fold	Type I ABC exporter transmembrane domain fold	Type I ABC exporter transmembrane domain fold	ABC_membrane