DrugDomain logoDrugDomain

N-(5-{4-[(1,1-dioxidothiomorpholin-4-yl)methyl]phenyl}[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide

P23458 — Tyrosine-protein kinase JAK1

← Back

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB14845

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
P23458DB148452HBnD5206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePK_Tyr_Ser-Thr
Show other predicted domains (75)
PDB IDDomain NameECOD IDX GroupH GroupT GroupF Group
3EYGe3eygA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
3EYHe3eyhA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4E4Le4e4lA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e4e4lE2206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e4e4lB2206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e4e4lD2206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4E4Ne4e4nB2206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e4e4nA2206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4E5We4e5wB2206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e4e5wA2206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4EHZe4ehzA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e4ehzC2206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e4ehzB2206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e4ehzD2206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4EI4e4ei4B2206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e4ei4A2206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4FK6e4fk6A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e4fk6B2206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4I5Ce4i5cB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e4i5cA2206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4IVBe4ivbA2206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e4ivbB2206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4IVCe4ivcA2206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e4ivcB2206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4IVDe4ivdA2206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e4ivdB2206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4K6Ze4k6zA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4K77e4k77A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e4k77B1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4L00e4l00A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e4l00B1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
4L01e4l01A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e4l01B1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
5E1Ee5e1eA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e5e1eB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
5HX8e5hx8A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e5hx8B1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
5IXDe5ixdA1197.1.1Acyl-CoA binding protein-likeAcyl-CoA binding protein-likeAcyl-CoA binding protein-likeFERM_M
e5ixdA2214.1.1SH2SH2SH2SH2
e5ixdA3220.1.1PH domain-likePH domain-likePH domain-likePH
e5ixdA4221.1.1beta-GraspUbiquitin-relatedUbiquitin-likeFer2
5IXIe5ixiA2197.1.1Acyl-CoA binding protein-likeAcyl-CoA binding protein-likeAcyl-CoA binding protein-likeFERM_M
e5ixiA3214.1.1SH2SH2SH2SH2
e5ixiA1220.1.1PH domain-likePH domain-likePH domain-likePH
e5ixiA4221.1.1beta-GraspUbiquitin-relatedUbiquitin-likeFer2
5KHWe5khwA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e5khwB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
5KHXe5khxA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
5L04e5l04A3197.1.1Acyl-CoA binding protein-likeAcyl-CoA binding protein-likeAcyl-CoA binding protein-likeFERM_M
e5l04A1214.1.1SH2SH2SH2SH2
e5l04A4220.1.1PH domain-likePH domain-likePH domain-likePH
e5l04A2221.1.1beta-GraspUbiquitin-relatedUbiquitin-likeFer2
5WO4e5wo4A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e5wo4B1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
6AAHe6aahA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e6aahB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
6BBUe6bbuA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
6C7Ye6c7yA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
6DBNe6dbnA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
6ELRe6elrA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e6elrB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
6GGHe6gghB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e6gghA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
6HZUe6hzuA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e6hzuB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
6N77e6n77A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e6n77B1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
6N78e6n78A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
6N79e6n79A1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
6N7Ae6n7aB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e6n7aA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
6N7Be6n7bA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
6N7Ce6n7cA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
e6n7cB1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase
6N7De6n7dA1206.1.1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePkinase

ECOD domains from experimental PDB structures interacting with ligand DB14845

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
No experimental ECOD data found