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P35968

KDR — Vascular endothelial growth factor receptor 2

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Lists of molecules and drugs that interact with protein P35968
DrugDomain DataDrugBank IDPDB LigandLigand NameChEMBLPubChemInChIKey
ExploreDB00141NAG
2-acetamido-2-deoxy-beta-D-glucopyranose
CHEMBL44787824139OVRNDRQMDRJTHS-FMDGEEDCSA-N
ExploreDB00398BAX
4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE
CHEMBL1336216239MLDQJTXFUGDVEO-UHFFFAOYSA-N
ExploreDB01268B49
N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide
CHEMBL5355329102WINHZLLDWRZWRT-ATVHPVEESA-N
ExploreDB04447DTT
2,3-DIHYDROXY-1,4-DITHIOBUTANE
CHEMBL406270439196VHJLVAABSRFDPM-IMJSIDKUSA-N
ExploreDB04727LIF
N-{4-[4-AMINO-6-(4-METHOXYPHENYL)FURO[2,3-D]PYRIMIDIN-5-YL]PHENYL}-N'-[2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL]UREA
CHEMBL1949115326956FGZIONRFHVNRJB-UHFFFAOYSA-N
ExploreDB04849n/a
Cediranib
n/an/an/a
ExploreDB04879n/a
Vatalanib
n/an/an/a
ExploreDB05075n/a
TG-100801
n/an/an/a
ExploreDB05575706
N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyridin-4-ylmethyl)amino]pyridine-3-carboxamide
CHEMBL57288111667893RAHBGWKEPAQNFF-UHFFFAOYSA-N
ExploreDB0598455J
1-methyl-5-({2-[5-(trifluoromethyl)-1H-imidazol-2-yl]pyridin-4-yl}oxy)-N-[4-(trifluoromethyl)phenyl]-1H-benzimidazol-2-amine
CHEMBL55875211656518YABJJWZLRMPFSI-UHFFFAOYSA-N
ExploreDB06080n/a
Linifanib
n/an/an/a
ExploreDB06436X2M
(3Z)-3-[(3,5-DIMETHYL-1H-PYRROL-2-YL)METHYLIDENE]-1,3-DIHYDRO-2H-INDOL-2-ONE
CHEMBL2767115329098WUWDLXZGHZSWQZ-WQLSENKSSA-N
ExploreDB06589n/a
Pazopanib
n/an/an/a
ExploreDB065952K2
PKC412
CHEMBL6085339829523BMGQWWVMWDBQGC-IIFHNQTCSA-N
ExploreDB06626AXI
AXITINIB
CHEMBL12899266450551RITAVMQDGBJQJZ-FMIVXFBMSA-N
ExploreDB06938276
4-[[2-[[4-chloro-3-(trifluoromethyl)phenyl]amino]-3H-benzimidazol-5-yl]oxy]-N-methyl-pyridine-2-carboxamide
CHEMBL39482611167118ZJLSMLDOCGOURY-UHFFFAOYSA-N
ExploreDB07183608
N-(4-phenoxyphenyl)-2-[(pyridin-4-ylmethyl)amino]nicotinamide
CHEMBL38517816040289CPVRYQAOUPSUDO-UHFFFAOYSA-N
ExploreDB07274887
N-cyclopropyl-6-[(6,7-dimethoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide
CHEMBL27219811441375ZATGFXTWDKIEKC-UHFFFAOYSA-N
ExploreDB07326A96
6-chloro-N-pyrimidin-5-yl-3-{[3-(trifluoromethyl)phenyl]amino}-1,2-benzisoxazole-7-carboxamide
CHEMBL49142923658582FEGRQUWSKADGSP-UHFFFAOYSA-N
ExploreDB07333AAX
N-(CYCLOPROPYLMETHYL)-4-(METHYLOXY)-3-({5-[3-(3-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-YL}AMINO)BENZENESULFONAMIDE
None4369498KRGKAARWVPUWSY-UHFFFAOYSA-N
ExploreDB07334AAZ
N-[5-(ETHYLSULFONYL)-2-METHOXYPHENYL]-5-[3-(2-PYRIDINYL)PHENYL]-1,3-OXAZOL-2-AMINE
CHEMBL1941764369497HTIZPBXCJPQDEM-UHFFFAOYSA-N
ExploreDB07514C19
3-(2-aminoquinazolin-6-yl)-1-(3,3-dimethylindolin-6-yl)-4-methylpyridin-2(1H)-one
CHEMBL49398624812717LHLGUOHREUTYTO-UHFFFAOYSA-N
ExploreDB07528C52
3-(2-aminoquinazolin-6-yl)-4-methyl-1-[3-(trifluoromethyl)phenyl]pyridin-2(1H)-one
CHEMBL50480524812719HXUZQEYFKAZBPX-UHFFFAOYSA-N
ExploreDB07537C92
N'-(6-aminopyridin-3-yl)-N-(2-cyclopentylethyl)-4-methyl-benzene-1,3-dicarboxamide
CHEMBL48743124812718CLEGTVIMOPPIBR-UHFFFAOYSA-N
ExploreDB08042KIM
N~4~-methyl-N~4~-(3-methyl-1H-indazol-6-yl)-N~2~-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine
None24941243FLXGQDHYCWXTAI-UHFFFAOYSA-N
ExploreDB08519SAV
N~4~-(3-methyl-1H-indazol-6-yl)-N~2~-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine
CHEMBL4790799822610SQQAPOSROFWHIB-UHFFFAOYSA-N
ExploreDB08875n/a
Cabozantinib
n/an/an/a
ExploreDB08896n/a
Regorafenib
n/an/an/a
ExploreDB089010LI
3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide
CHEMBL117183724826799PHXJVRSECIGDHY-UHFFFAOYSA-N
ExploreDB09078LEV
4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide
CHEMBL12896019823820WOSKHXYHFSIKNG-UHFFFAOYSA-N
ExploreDB09079XIN
methyl (3Z)-3-{[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}phenyl)amino](phenyl)methylidene}-2-oxo-2,3-dihydro-1H-indole-6-carboxylate
CHEMBL5028359809715XZXHXSATPCNXJR-ZIADKAODSA-N
ExploreDB09462GOL
GLYCEROL
CHEMBL692753PEDCQBHIVMGVHV-UHFFFAOYSA-N
ExploreDB11800AV9
TIVOZANIB
CHEMBL12894949911830SPMVMDHWKHCIDT-UHFFFAOYSA-N
ExploreDB120102RC
[6-({5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl}amino)-2,2-dimethyl-3-oxo-2,3-dihydro-4H-pyrido[3,2-b][1,4]oxazin-4-yl]methyl dihydrogen phosphate
CHEMBL210383011671467GKDRMWXFWHEQQT-UHFFFAOYSA-N
ExploreDB121475SF
~{N}'-(3,5-dimethoxyphenyl)-~{N}'-[3-(1-methylpyrazol-4-yl)quinoxalin-6-yl]-~{N}-propan-2-yl-ethane-1,2-diamine
CHEMBL354537667462786OLAHOMJCDNXHFI-UHFFFAOYSA-N
ExploreDB1230788Z
N-(3-fluoro-4-{[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
CHEMBL123060942642645CXQHYVUVSFXTMY-UHFFFAOYSA-N
ExploreDB14511ACT
ACETATE ION
None175QTBSBXVTEAMEQO-UHFFFAOYSA-M
ExploreDB14546SO4
SULFATE ION
None1117QAOWNCQODCNURD-UHFFFAOYSA-L
ExploreDB14840n/a
Ripretinib
n/an/an/a
ExploreDB15822Q4J
Pralsetinib
CHEMBL4297597n/aGBLBJPZSROAGMF-BATDWUPUSA-N
ExploreNone00J
N,2-DIMETHYL-6-{[7-(2-MORPHOLIN-4-YLETHOXY)QUINOLIN-4-YL]OXY}-1-BENZOFURAN-3-CARBOXAMIDE
CHEMBL173869711236560LGXVKMDGSIWEHL-UHFFFAOYSA-N
ExploreNone03X
N-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophenyl}-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide
CHEMBL203189356604907SBLMCLDRWJNEJK-UHFFFAOYSA-N
ExploreNone0JA
2-chloro-3-(1-cyanocyclopropyl)-N-[5-({2-[(cyclopropylcarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}oxy)-2-fluorophenyl]benzamide
CHEMBL206374325206185MDPMAXSABUPRJI-UHFFFAOYSA-N
ExploreNone0KF
N-[3-({2-[(cyclopropylcarbonyl)amino]imidazo[1,2-b]pyridazin-6-yl}oxy)phenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide
CHEMBL234899657505507IFFBOVLYGJAFKB-UHFFFAOYSA-N
ExploreNone2RL
N-(4-CHLOROPHENYL)-7-[(6,7-DIMETHOXYQUINOLIN-4-YL)OXY]-2,3-DIHYDRO-1,4-BENZOXAZINE-4-CARBOXAMIDE
CHEMBL27054811375301RNHWXYKRVZUXGO-UHFFFAOYSA-N
ExploreNone42Q
1-{2-fluoro-4-[(5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)oxy]phenyl}-3-[3-(trifluoromethyl)phenyl]urea
CHEMBL125400715949613TWOLOZGQZKJZKJ-UHFFFAOYSA-N
ExploreNone4TT
4,5,6,11-tetrahydro-1H-pyrazolo[4',3':6,7]cyclohepta[1,2-b]indole
CHEMBL1929485135566619HBWXPQZQCDQNND-UHFFFAOYSA-N
ExploreNone5T2
2-(pyridin-4-ylmethylamino)-~{N}-[3-(trifluoromethyl)phenyl]benzamide
CHEMBL1538436398883BLAFVGLBBOPRLP-UHFFFAOYSA-N
ExploreNone857
4-({2-[(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]methoxy}phenyl)amino]-1,3-benzoxazol-5-yl}oxy)-N-methylpyridine-2-carboxamide
CHEMBL23156811620410KMNCFOUKJYOZIF-KRWDZBQOSA-N
ExploreNone900
N-(4-chlorophenyl)-6-[(6,7-dimethoxyquinolin-4-yl)oxy]naphthalene-1-carboxamide
CHEMBL42974324757938WUBFAXNVDMCVIO-UHFFFAOYSA-N
ExploreNone994
4-(2-anilinopyridin-3-yl)-N-(3,4,5-trimethoxyphenyl)-1,3,5-triazin-2-amine
CHEMBL21805716040288YRSYWYSGZPRSOP-UHFFFAOYSA-N
ExploreNoneBPK
{3-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methoxy]phenyl}methanol
CHEMBL206962511140977UPVJJOGZAKVERR-UHFFFAOYSA-N
ExploreNoneCA
CALCIUM ION
None271BHPQYMZQTOCNFJ-UHFFFAOYSA-N
ExploreNoneCAC
CACODYLATE ION
None167250OGGXGZAMXPVRFZ-UHFFFAOYSA-M
ExploreNoneCS
CESIUM ION
None104967NCMHKCKGHRPLCM-UHFFFAOYSA-N
ExploreNoneEDO
1,2-ETHANEDIOL
CHEMBL457299174LYCAIKOWRPUZTN-UHFFFAOYSA-N
ExploreNoneF82
2-[4-(6,7-dimethoxyquinazolin-4-yl)oxy-2-methoxy-phenyl]-~{N}-(1-propan-2-ylpyrazol-4-yl)ethanamide
CHEMBL4212563134814266INYIBEJMXPAZLV-UHFFFAOYSA-N
ExploreNoneF88
~{N}-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-2-(1-ethylpyrazol-4-yl)ethanamide
CHEMBL4213606134814267LQRLWWAVCUCERB-UHFFFAOYSA-N
ExploreNoneF8B
~{N}-[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]-2-(4-propan-2-yl-1,2,3-triazol-1-yl)ethanamide
CHEMBL4214769134814268VOSCKXNNVDOPMN-UHFFFAOYSA-N
ExploreNoneGIG
METHYL (5-{4-[({[2-FLUORO-5-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-1H-BENZIMIDAZOL-2-YL)CARBAMATE
CHEMBL3960569935852KADQEUOYNAPXRD-UHFFFAOYSA-N
ExploreNoneHG
MERCURY (II) ION
None26623BQPIGGFYSBELGY-UHFFFAOYSA-N
ExploreNoneK11
N-[4-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl}oxy)naphthalen-1-yl]-6-(trifluoromethyl)-1H-benzimidazol-2-amine
CHEMBL46332316731782VIHXUAKPZPXVSW-UHFFFAOYSA-N
ExploreNoneO35
~{N}-[3-[(dimethylamino)methyl]-5-methyl-phenyl]-2-[3-methoxy-5-(7-methoxyquinolin-4-yl)oxy-pyridin-2-yl]ethanamide
None146037621MALCRTBNJLPDJJ-UHFFFAOYSA-N
ExploreNoneO3E
~{N}-(4,4-dimethyl-2-prop-1-ynyl-3,1-benzoxazin-6-yl)-2-[3-methoxy-5-(7-methoxyquinolin-4-yl)oxy-pyridin-2-yl]ethanamide
None146037624RBASQIFWXZMGHR-UHFFFAOYSA-N
ExploreNoneRAJ
N-{3-[3-(DIMETHYLAMINO)PROPYL]-5-(TRIFLUOROMETHYL)PHENYL}-4-METHYL-3-[(3-PYRIMIDIN-4-YLPYRIDIN-2-YL)AMINO]BENZAMIDE
CHEMBL22148411497471OHHGYJBFPVJURR-UHFFFAOYSA-N