DrugDomain logoDrugDomain

3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide

P35968 — Vascular endothelial growth factor receptor 2

← Back

Attributes

UniProt ID
P35968
Protein Name
Vascular endothelial growth factor receptor 2
Ligand Name
3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide
DrugBank ID
DB08901
PDB Ligand Accession
0LI
ChEMBL ID
CHEMBL1171837
PubChem ID
24826799
InChIKey
PHXJVRSECIGDHY-UHFFFAOYSA-N
SMILES
Cc1ccc(cc1C#Cc2cnc3n2nccc3)C(=O)Nc4ccc(c(c4)C(F)(F)F)CN5CCN(CC5)C
Drug Action
inhibitor
Affinity Metrics
ki:1.5 nM
ic50:1.5 nM