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(2S)-N~1~-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide

P42336 — Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand DB12015

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand DB12015

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P42336DB120154jps1LTA1102e4jpsA1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePI3_PI4_kinase
P42336DB120157myo1LTA1101e7myoA1Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePI3_PI4_kinase
P42336DB120157pg61LTA1101e7pg6A2Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePI3_PI4_kinase
P42336DB120158gua1LTA1101e8guaA4Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePI3_PI4_kinase
P42336DB120158gub1LTA1101e8gubA4Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePI3_PI4_kinase
P42336DB120158gud1LTA1101e8gudA2Protein kinase/SAICAR synthase/ATP-graspProtein kinase/SAICAR synthase/ATP-graspProtein kinasePI3_PI4_kinase