DrugDomain logoDrugDomain

3'-[(2R)-4-(2,4-diamino-6-ethylpyrimidin-5-yl)but-3-yn-2-yl]-5'-methoxy[1,1'-biphenyl]-4-carboxylic acid

P9WNX1 Dihydrofolate reductase

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand G6Y

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand G6Y

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
P9WNX1n/a6ddpG6YA202e6ddpA1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
P9WNX1n/a6ddpG6YB202e6ddpB1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
P9WNX1n/a6ddpG6YC201e6ddpC1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1
P9WNX1n/a6ddpG6YD202e6ddpD1Dihydrofolate reductasesDihydrofolate reductasesDihydrofolate reductasesDHFR_1