NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Q07422 — Bifunctional dihydrofolate reductase-thymidylate synthase
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand DB02338
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand DB02338
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| Q07422 | DB02338 | 4eck | NDP | A | 704 | e4eckA2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 4eck | NDP | B | 704 | e4eckB2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 4eil | NDP | A | 704 | e4eilA3 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 4eil | NDP | A | 704 | e4eilG5 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 4eil | NDP | B | 704 | e4eilB2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 4eil | NDP | C | 704 | e4eilC5 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 4eil | NDP | D | 704 | e4eilD2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 4eil | NDP | E | 704 | e4eilE5 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 4eil | NDP | F | 704 | e4eilF3 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 4eil | NDP | G | 704 | e4eilG5 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 4eil | NDP | H | 704 | e4eilH2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 4ky4 | NDP | A | 703 | e4ky4A2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 4ky4 | NDP | B | 703 | e4ky4B2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 4ky4 | NDP | C | 703 | e4ky4C2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 4ky4 | NDP | D | 703 | e4ky4D2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 4ky4 | NDP | E | 703 | e4ky4E2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 4ky4 | NDP | F | 703 | e4ky4F2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 4ky4 | NDP | G | 703 | e4ky4G2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 4ky4 | NDP | H | 703 | e4ky4H2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 4kya | NDP | A | 704 | e4kyaA2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 4kya | NDP | B | 704 | e4kyaB2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 4kya | NDP | C | 704 | e4kyaC2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 4kya | NDP | D | 704 | e4kyaD2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 4kya | NDP | E | 704 | e4kyaE2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 4kya | NDP | F | 704 | e4kyaF2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 4kya | NDP | G | 704 | e4kyaG2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 4kya | NDP | H | 704 | e4kyaH3 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 5t0l | NDP | A | 702 | e5t0lA1 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 5t0l | NDP | B | 702 | e5t0lB2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 6aog | NDP | A | 702 | e6aogA1 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 6aog | NDP | B | 702 | e6aogB1 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 6aoh | NDP | A | 702 | e6aohA2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 6aoh | NDP | B | 702 | e6aohB2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 6aoi | NDP | A | 702 | e6aoiA1 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 6aoi | NDP | B | 702 | e6aoiB2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 6n1s | NDP | A | 702 | e6n1sA1 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 6n1s | NDP | B | 702 | e6n1sB2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 6n1t | NDP | A | 702 | e6n1tA2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 6n1t | NDP | B | 702 | e6n1tB1 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 7fgw | NDP | A | 701 | e7fgwA2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 7fgw | NDP | B | 701 | e7fgwB2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 7fgw | NDP | C | 701 | e7fgwC2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 7fgw | NDP | D | 701 | e7fgwD1 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 7fgx | NDP | A | 701 | e7fgxA2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 7fgx | NDP | B | 701 | e7fgxB2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 7fgx | NDP | C | 701 | e7fgxC1 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 7fgx | NDP | D | 701 | e7fgxD2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 7fgy | NDP | A | 701 | e7fgyA2 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 7fgy | NDP | B | 701 | e7fgyB1 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 7fgy | NDP | C | 701 | e7fgyC1 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |
| Q07422 | DB02338 | 7fgy | NDP | D | 701 | e7fgyD1 | Dihydrofolate reductases | Dihydrofolate reductases | Dihydrofolate reductases | DHFR_1 |