6-[(R)-(4-chlorophenyl)(methoxy)(1-methyl-1H-imidazol-5-yl)methyl]-4-(2,6-difluorophenyl)-1-methylquinolin-2(1H)-one
Q385E8 — Lanosterol 14-alpha-demethylase
ECOD Domain Annotations
ECOD domains from AlphaFold model interacting with ligand JKF
| UniProt | DrugBank | PDB Ligand | Domain Label | ECOD ID | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|
| No predicted ECOD data found | ||||||||
ECOD domains from experimental PDB structures interacting with ligand JKF
| UniProt | DrugBank | PDB ID | Ligand Acc. | Chain | Res No. | Exp. Domain | X Group | H Group | T Group | F Group |
|---|---|---|---|---|---|---|---|---|---|---|
| Q385E8 | n/a | 3tik | JKF | A | 490 | e3tikA1 | Cytochrome P450 | Cytochrome P450 | Cytochrome P450 | p450 |
| Q385E8 | n/a | 3tik | JKF | B | 490 | e3tikB1 | Cytochrome P450 | Cytochrome P450 | Cytochrome P450 | p450 |
| Q385E8 | n/a | 3tik | JKF | C | 490 | e3tikC1 | Cytochrome P450 | Cytochrome P450 | Cytochrome P450 | p450 |
| Q385E8 | n/a | 3tik | JKF | D | 490 | e3tikD1 | Cytochrome P450 | Cytochrome P450 | Cytochrome P450 | p450 |