2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE

Q5KWC1 — DNA polymerase I

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand D3T

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand D3T

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
Q5KWC1	n/a	2hhw	D3T	A	881	e2hhwA1	helical bundle in Bacillus stearothermophilus-like DNA polymerase I	helical bundle in Bacillus stearothermophilus-like DNA polymerase I	helical bundle in Bacillus stearothermophilus-like DNA polymerase I	DNA_pol_A
Q5KWC1	n/a	2hhw	D3T	A	881	e2hhwA2	fingers domain in bacteriophage RB69-like DNA polymerase I	fingers domain in bacteriophage RB69-like DNA polymerase I	fingers domain in bacteriophage RB69-like DNA polymerase I	DNA_pol_A
Q5KWC1	n/a	2hhw	D3T	A	881	e2hhwA3	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	DNA_pol_A
Q5KWC1	n/a	2hhw	D3T	D	880	e2hhwD1	helical bundle in Bacillus stearothermophilus-like DNA polymerase I	helical bundle in Bacillus stearothermophilus-like DNA polymerase I	helical bundle in Bacillus stearothermophilus-like DNA polymerase I	DNA_pol_A
Q5KWC1	n/a	2hhw	D3T	D	880	e2hhwD2	fingers domain in bacteriophage RB69-like DNA polymerase I	fingers domain in bacteriophage RB69-like DNA polymerase I	fingers domain in bacteriophage RB69-like DNA polymerase I	DNA_pol_A
Q5KWC1	n/a	2hhw	D3T	D	880	e2hhwD3	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	DNA_pol_A
Q5KWC1	n/a	3hp6	D3T	A	201	e3hp6A1	helical bundle in Bacillus stearothermophilus-like DNA polymerase I	helical bundle in Bacillus stearothermophilus-like DNA polymerase I	helical bundle in Bacillus stearothermophilus-like DNA polymerase I	DNA_pol_A
Q5KWC1	n/a	3hp6	D3T	A	201	e3hp6A2	fingers domain in bacteriophage RB69-like DNA polymerase I	fingers domain in bacteriophage RB69-like DNA polymerase I	fingers domain in bacteriophage RB69-like DNA polymerase I	DNA_pol_A
Q5KWC1	n/a	3hp6	D3T	A	201	e3hp6A3	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	DNA_pol_A
Q5KWC1	n/a	3hp6	D3T	D	202	e3hp6D1	helical bundle in Bacillus stearothermophilus-like DNA polymerase I	helical bundle in Bacillus stearothermophilus-like DNA polymerase I	helical bundle in Bacillus stearothermophilus-like DNA polymerase I	DNA_pol_A
Q5KWC1	n/a	3hp6	D3T	D	202	e3hp6D2	fingers domain in bacteriophage RB69-like DNA polymerase I	fingers domain in bacteriophage RB69-like DNA polymerase I	fingers domain in bacteriophage RB69-like DNA polymerase I	DNA_pol_A
Q5KWC1	n/a	3hp6	D3T	D	202	e3hp6D3	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	DNA_pol_A
Q5KWC1	n/a	3pv8	D3T	A	201	e3pv8A1	helical bundle in Bacillus stearothermophilus-like DNA polymerase I	helical bundle in Bacillus stearothermophilus-like DNA polymerase I	helical bundle in Bacillus stearothermophilus-like DNA polymerase I	DNA_pol_A
Q5KWC1	n/a	3pv8	D3T	A	201	e3pv8A2	fingers domain in bacteriophage RB69-like DNA polymerase I	fingers domain in bacteriophage RB69-like DNA polymerase I	fingers domain in bacteriophage RB69-like DNA polymerase I	DNA_pol_A
Q5KWC1	n/a	3pv8	D3T	A	201	e3pv8A3	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	DNA_pol_A
Q5KWC1	n/a	3pv8	D3T	D	202	e3pv8D1	helical bundle in Bacillus stearothermophilus-like DNA polymerase I	helical bundle in Bacillus stearothermophilus-like DNA polymerase I	helical bundle in Bacillus stearothermophilus-like DNA polymerase I	DNA_pol_A
Q5KWC1	n/a	3pv8	D3T	D	202	e3pv8D2	fingers domain in bacteriophage RB69-like DNA polymerase I	fingers domain in bacteriophage RB69-like DNA polymerase I	fingers domain in bacteriophage RB69-like DNA polymerase I	DNA_pol_A
Q5KWC1	n/a	3pv8	D3T	D	202	e3pv8D3	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	DNA_pol_A
Q5KWC1	n/a	4ez9	D3T	D	901	e4ez9D1	helical bundle in Bacillus stearothermophilus-like DNA polymerase I	helical bundle in Bacillus stearothermophilus-like DNA polymerase I	helical bundle in Bacillus stearothermophilus-like DNA polymerase I	DNA_pol_A
Q5KWC1	n/a	4ez9	D3T	D	901	e4ez9D2	fingers domain in bacteriophage RB69-like DNA polymerase I	fingers domain in bacteriophage RB69-like DNA polymerase I	fingers domain in bacteriophage RB69-like DNA polymerase I	DNA_pol_A
Q5KWC1	n/a	4ez9	D3T	D	901	e4ez9D3	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	DNA_pol_A
Q5KWC1	n/a	4f3o	D3T	D	901	e4f3oD1	helical bundle in Bacillus stearothermophilus-like DNA polymerase I	helical bundle in Bacillus stearothermophilus-like DNA polymerase I	helical bundle in Bacillus stearothermophilus-like DNA polymerase I	DNA_pol_A
Q5KWC1	n/a	4f3o	D3T	D	901	e4f3oD2	fingers domain in bacteriophage RB69-like DNA polymerase I	fingers domain in bacteriophage RB69-like DNA polymerase I	fingers domain in bacteriophage RB69-like DNA polymerase I	DNA_pol_A
Q5KWC1	n/a	4f3o	D3T	D	901	e4f3oD3	Alpha-beta plaits	Adenylyl and guanylyl cyclase catalytic domain-like	Adenylyl and guanylyl cyclase catalytic domain-like	DNA_pol_A