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3-[[(2~{S},3~{a}~{R},5~{R},6~{R},6~{a}~{R})-5-[[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-oxidanyl-phosphoryl]oxymethyl]-2-[[(5~{S})-6-[[(2~{S})-3-(1~{H}-indol-3-yl)-1-oxidanylidene-1-(propan-2-ylamino)propan-2-yl]amino]-6-oxidanylidene-5-(phenylmethoxycarbonylamino)hexyl]amino]-6-oxidanyl-3~{a},5,6,6~{a}-tetrahydrofuro[2,3-d][1,3]oxathiol-2-yl]amino]propanoic acid

Q6DHI5 — NAD-dependent protein deacylase sirtuin-5, mitochondrial

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ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand BVT

UniProtDrugBankPDB LigandDomain LabelECOD IDX GroupH GroupT GroupF Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand BVT

UniProtDrugBankPDB IDLigand Acc.ChainRes No.Exp. DomainX GroupH GroupT GroupF Group
Q6DHI5n/a6eo0BVTA304e6eo0A1Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q6DHI5n/a6eo0BVTA304e6eo0A2Rubredoxin-likeRubredoxin-relatedRubredoxin-relatedn/a
Q6DHI5n/a6eo0BVTA304e6eo0C1Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q6DHI5n/a6eo0BVTB303e6eo0B1Rubredoxin-likeRubredoxin-relatedRubredoxin-relatedn/a
Q6DHI5n/a6eo0BVTB303e6eo0B2Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q6DHI5n/a6eo0BVTB303e6eo0D1Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q6DHI5n/a6eo0BVTC303e6eo0A1Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q6DHI5n/a6eo0BVTC303e6eo0C1Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q6DHI5n/a6eo0BVTC303e6eo0C2Rubredoxin-likeRubredoxin-relatedRubredoxin-relatedn/a
Q6DHI5n/a6eo0BVTD303e6eo0B2Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q6DHI5n/a6eo0BVTD303e6eo0D1Rossmann-likeRossmann-relatedDHS-like NAD/FAD-binding domainSIR2
Q6DHI5n/a6eo0BVTD303e6eo0D2Rubredoxin-likeRubredoxin-relatedRubredoxin-relatedn/a