5-[[3,5-bis(chloranyl)phenyl]sulfonylamino]-2-[(5-bromanyl-4-fluoranyl-2-methyl-phenyl)sulfamoyl]benzoic acid

Q8N6T7 — NAD-dependent protein deacylase sirtuin-6

ECOD Domain Annotations

ECOD domains from AlphaFold model interacting with ligand 8L9

UniProt	DrugBank	PDB Ligand	Domain Label	ECOD ID	X Group	H Group	T Group	F Group
No predicted ECOD data found

ECOD domains from experimental PDB structures interacting with ligand 8L9

UniProt	DrugBank	PDB ID	Ligand Acc.	Chain	Res No.	Exp. Domain	X Group	H Group	T Group	F Group
Q8N6T7	n/a	5y2f	8L9	A	402	e5y2fA1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	n/a
Q8N6T7	n/a	5y2f	8L9	A	402	e5y2fA2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	6xv1	8L9	A	403	e6xv1A1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	n/a
Q8N6T7	n/a	6xv1	8L9	A	403	e6xv1A2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	6xvg	8L9	A	404	e6xvgA1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	6xvg	8L9	A	404	e6xvgA2	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	n/a
Q8N6T7	n/a	6xvg	8L9	B	404	e6xvgB1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	6xvg	8L9	B	404	e6xvgB2	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	n/a
Q8N6T7	n/a	6xvg	8L9	C	1006	e6xvgC1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	n/a
Q8N6T7	n/a	6xvg	8L9	C	1006	e6xvgC2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	6xvg	8L9	C	1006	e6xvgD1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	6xvg	8L9	D	404	e6xvgD1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	6xvg	8L9	D	404	e6xvgD2	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	n/a
Q8N6T7	n/a	6xvg	8L9	E	705	e6xvgB1	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	6xvg	8L9	E	705	e6xvgE1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	n/a
Q8N6T7	n/a	6xvg	8L9	E	705	e6xvgE2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	6xvg	8L9	F	403	e6xvgC2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	6xvg	8L9	F	403	e6xvgE2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	6xvg	8L9	F	403	e6xvgF1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	n/a
Q8N6T7	n/a	6xvg	8L9	F	403	e6xvgF2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2
Q8N6T7	n/a	7cl1	8L9	A	403	e7cl1A1	Rubredoxin-like	Rubredoxin-related	Rubredoxin-related	n/a
Q8N6T7	n/a	7cl1	8L9	A	403	e7cl1A2	Rossmann-like	Rossmann-related	DHS-like NAD/FAD-binding domain	SIR2